Nortriptyline
TL;DR: Nortriptyline (CAS 72-69-5) is a chemical compound with molecular formula C19H21N and molecular weight 263.1674 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
N-methyl-3-(2-tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,11,13-hexaenylidene)propan-1-amine
Also Known As: nortriptyline, Noramitriptyline, Desitriptilina, Aventyl, Avantyl
Application Areas
Top 5 of 19 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C19H21N |
| Molecular Weight | 263.1674 g/mol |
| XLogP | 4.5 |
| Topological Polar Surface Area (TPSA) | 12.0 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 1 |
| Rotatable Bonds | 3 |
| Exact Mass | 263.1674 Da |
| Heavy Atoms | 20 |
| Complexity | 307.0 |
| Melting Point | 58 |
| Boiling Point | 396.62 |
| Solubility | 0.00087 |
| SMILES | CNCCC=C1C2=CC=CC=C2CCC3=CC=CC=C31 |
| InChIKey | PHVGLTMQBUFIQQ-UHFFFAOYSA-N |
Product Description
Applications: Nortriptyline is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
Nortriptyline (CAS 72-69-5) is a pharmaceutical intermediate with the molecular formula C19H21N and a molecular weight of 263.17 g/mol. Key physical properties include a solubility: 0.00087. Synonyms include nortriptyline and Noramitriptyline.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Nortriptyline
Property Insights of Nortriptyline
The XLogP value of 4.5 indicates that Nortriptyline is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 12.0 Ų, Nortriptyline exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Nortriptyline has 1 hydrogen bond donor(s) and 1 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Nortriptyline?
The CAS number of Nortriptyline is 72-69-5.
What is the molecular formula of Nortriptyline?
The molecular formula of Nortriptyline is C19H21N.
What is the molecular weight of Nortriptyline?
The molecular weight of Nortriptyline is 263.1674 g/mol.
What are the applications of Nortriptyline?
Nortriptyline is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and...
Where can I buy Nortriptyline?
You can request a quote for Nortriptyline directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Nortriptyline?
Yes, CoreyChem provides custom synthesis services for Nortriptyline and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.