Felodipine
TL;DR: Felodipine (CAS 72509-76-3) is a chemical compound with molecular formula C18H19Cl2NO4 and molecular weight 383.06912 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
5-O-ethyl 3-O-methyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate
Also Known As: felodipine, Plendil, Flodil, Splendil, Feloday
Application Areas
Top 5 of 16 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C18H19Cl2NO4 |
| Molecular Weight | 383.06912 g/mol |
| XLogP | 3.9 |
| Topological Polar Surface Area (TPSA) | 64.6 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 6 |
| Exact Mass | 383.06912 Da |
| Heavy Atoms | 25 |
| Complexity | 614.0 |
| Melting Point | 145 |
| Solubility | 19.7 |
| SMILES | CCOC(=O)C1=C(NC(=C(C1C2=C(C(=CC=C2)Cl)Cl)C(=O)OC)C)C |
| InChIKey | RZTAMFZIAATZDJ-UHFFFAOYSA-N |
Product Description
Applications: Felodipine is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies Felodipine (CAS 72509-76-3) with custom synthesis available from milligram to multi-kilogram scale, supported by COA, MSDS, and HPLC/NMR/MS documentation.
Felodipine is a pharmaceutical intermediate identified by CAS number 72509-76-3 and the molecular formula C18H19Cl2NO4 and a molecular weight of 383.07 g/mol. Physically, the compound has a solubility: 19.7. It is also known as felodipine and Plendil.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Felodipine
Property Insights of Felodipine
The XLogP value of 3.9 indicates that Felodipine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 64.6 Ų falls within the moderate polarity range, balancing permeability and solubility for Felodipine. Following Lipinski's Rule of Five, Felodipine has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Felodipine?
The CAS number of Felodipine is 72509-76-3.
What is the molecular formula of Felodipine?
The molecular formula of Felodipine is C18H19Cl2NO4.
What is the molecular weight of Felodipine?
The molecular weight of Felodipine is 383.06912 g/mol.
What are the applications of Felodipine?
Felodipine is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies Felodipine (CAS 72509-76-3) with custom...
Where can I buy Felodipine?
You can request a quote for Felodipine directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Felodipine?
Yes, CoreyChem provides custom synthesis services for Felodipine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.