Hydrocortisone Aceponate
TL;DR: Hydrocortisone Aceponate (CAS 74050-20-7) is a chemical compound with molecular formula C26H36O7 and molecular weight 460.2461 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
[(8S,9S,10R,11S,13S,14S,17R)-17-(2-acetyloxyacetyl)-11-hydroxy-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl] propanoate
Also Known As: Hydrocortisone aceponate, Efficort, hydrocortisone, Cortavance, retef
Application Areas
Top 5 of 4 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C26H36O7 |
| Molecular Weight | 460.2461 g/mol |
| XLogP | 3.3 |
| Topological Polar Surface Area (TPSA) | 107.0 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 7 |
| Exact Mass | 460.2461 Da |
| Heavy Atoms | 33 |
| Complexity | 906.0 |
| SMILES | CCC(=O)O[C@@]1(CC[C@@H]2[C@@]1(C[C@@H]([C@H]3[C@H]2CCC4=CC(=O)CC[C@]34C)O)C)C(=O)COC(=O)C |
| InChIKey | MFBMYAOAMQLLPK-FZNHGJLXSA-N |
Chemical Property Profile of Hydrocortisone Aceponate
Property Insights of Hydrocortisone Aceponate
The XLogP value of 3.3 indicates that Hydrocortisone Aceponate is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 107.0 Ų falls within the moderate polarity range, balancing permeability and solubility for Hydrocortisone Aceponate. Following Lipinski's Rule of Five, Hydrocortisone Aceponate has 1 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Hydrocortisone Aceponate?
The CAS number of Hydrocortisone Aceponate is 74050-20-7.
What is the molecular formula of Hydrocortisone Aceponate?
The molecular formula of Hydrocortisone Aceponate is C26H36O7.
What is the molecular weight of Hydrocortisone Aceponate?
The molecular weight of Hydrocortisone Aceponate is 460.2461 g/mol.
Where can I buy Hydrocortisone Aceponate?
You can request a quote for Hydrocortisone Aceponate directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Hydrocortisone Aceponate?
Yes, CoreyChem provides custom synthesis services for Hydrocortisone Aceponate and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.