Tegafur-Uracil
TL;DR: Tegafur-Uracil (CAS 74578-38-4) is a chemical compound with molecular formula C12H13FN4O5 and molecular weight 312.087 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
5-fluoro-1-(oxolan-2-yl)pyrimidine-2,4-dione;1H-pyrimidine-2,4-dione
Also Known As: Tegafur-Uracil, Uftoral, Ufur, 1-Uft protocol, Youfuding
Application Areas
Top 5 of 8 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C12H13FN4O5 |
| Molecular Weight | 312.087 g/mol |
| XLogP | -0.95 |
| Topological Polar Surface Area (TPSA) | 117.0 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 1 |
| Exact Mass | 312.087 Da |
| Heavy Atoms | 22 |
| Complexity | 477.0 |
| SMILES | C1CC(OC1)N2C=C(C(=O)NC2=O)F.C1=CNC(=O)NC1=O |
| InChIKey | DHMYGZIEILLVNR-UHFFFAOYSA-N |
Chemical Property Profile of Tegafur-Uracil
Property Insights of Tegafur-Uracil
The XLogP value of -0.95 indicates that Tegafur-Uracil is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 117.0 Ų falls within the moderate polarity range, balancing permeability and solubility for Tegafur-Uracil. Following Lipinski's Rule of Five, Tegafur-Uracil has 3 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Tegafur-Uracil?
The CAS number of Tegafur-Uracil is 74578-38-4.
What is the molecular formula of Tegafur-Uracil?
The molecular formula of Tegafur-Uracil is C12H13FN4O5.
What is the molecular weight of Tegafur-Uracil?
The molecular weight of Tegafur-Uracil is 312.087 g/mol.
Where can I buy Tegafur-Uracil?
You can request a quote for Tegafur-Uracil directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Tegafur-Uracil?
Yes, CoreyChem provides custom synthesis services for Tegafur-Uracil and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.