Difluoromethane
TL;DR: Difluoromethane (CAS 75-10-5) is a chemical compound with molecular formula CH2F2 and molecular weight 52.012455 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
difluoromethane
Also Known As: DIFLUOROMETHANE, Methylene difluoride, Methane, difluoro-, Genetron 32, Methylene fluoride
Application Areas
Top 5 of 22 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | CH2F2 |
| Molecular Weight | 52.012455 g/mol |
| XLogP | 1.0 |
| Topological Polar Surface Area (TPSA) | 0.0 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 0 |
| Exact Mass | 52.012455 Da |
| Heavy Atoms | 3 |
| Complexity | 2.0 |
| Melting Point | -136.8 °C |
| Boiling Point | -51.65 °C |
| Density | 0.961 at 25 °C; 1.052 at 0 °C (liquid) |
| Vapor Pressure | 1.26X10+4 mm Hg at 25 °C |
| Solubility | In water, 0.44% at 25 °C |
| SMILES | C(F)F |
| InChIKey | RWRIWBAIICGTTQ-UHFFFAOYSA-N |
Product Description
Applications: Difluoromethane is used in heterocycle construction in medicinal chemistry and agrochemical discovery, as well as pharmaceutical synthesis routes and API production. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
A heterocyclic building block supplied by CoreyChem, Difluoromethane (CAS 75-10-5) has the molecular formula CH2F2 and a molecular weight of 52.01 g/mol. Reported properties include a density of 0.961 at 25 °C; 1.052 at 0 °C (liquid) g/cm³, a solubility: In water, 0.44% at 25 °C. Synonyms include DIFLUOROMETHANE and Methylene difluoride.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Difluoromethane
Property Insights of Difluoromethane
The XLogP value of 1.0 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Difluoromethane. With a topological polar surface area (TPSA) of 0.0 Ų, Difluoromethane exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Difluoromethane has 0 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Difluoromethane?
The CAS number of Difluoromethane is 75-10-5.
What is the molecular formula of Difluoromethane?
The molecular formula of Difluoromethane is CH2F2.
What is the molecular weight of Difluoromethane?
The molecular weight of Difluoromethane is 52.012455 g/mol.
What are the applications of Difluoromethane?
Difluoromethane is used in heterocycle construction in medicinal chemistry and agrochemical discovery, as well as pharmaceutical synthesis routes and API production. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and...
Where can I buy Difluoromethane?
You can request a quote for Difluoromethane directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Difluoromethane?
Yes, CoreyChem provides custom synthesis services for Difluoromethane and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.