Bromoform
TL;DR: Bromoform (CAS 75-25-2) is a chemical compound with molecular formula CHBr3 and molecular weight 249.76283 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
bromoform
Also Known As: Bromoform, tribromomethane, Methane, tribromo-, Tribrommethan, Methyl tribromide
Application Areas
Top 5 of 22 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | CHBr3 |
| Molecular Weight | 249.76283 g/mol |
| XLogP | 2.8 |
| Topological Polar Surface Area (TPSA) | 0.0 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 0 |
| Rotatable Bonds | 0 |
| Exact Mass | 251.76079 Da |
| Heavy Atoms | 4 |
| Complexity | 8.0 |
| Melting Point | 48 °F (NTP, 1992) |
| Boiling Point | 301.1 °F at 760 mmHg (NTP, 1992) |
| Density | 2.8912 at 68 °F (USCG, 1999) - Denser than water; will sink |
| Vapor Pressure | 5 mmHg at 68 °F ; 5.6 mmHg at 77 °F (NTP, 1992) |
| Refractive Index | Index of refraction: 1.5948 at 25 °C/D |
| Solubility | less than 0.1 mg/mL at 72.5 °F (NTP, 1992) |
| SMILES | C(Br)(Br)Br |
| InChIKey | DIKBFYAXUHHXCS-UHFFFAOYSA-N |
Product Description
Applications: Bromoform is used in heterocycle construction in medicinal chemistry and agrochemical discovery, as well as pharmaceutical synthesis routes and API production. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies Bromoform (CAS 75-25-2) with custom synthesis available from milligram to multi-kilogram scale, supported by COA, MSDS, and HPLC/NMR/MS documentation.
A heterocyclic building block supplied by CoreyChem, Bromoform (CAS 75-25-2) has the molecular formula CHBr3 and a molecular weight of 249.76 g/mol. Reported properties include a density of 2.8912 at 68 °F (USCG, 1999) - Denser than water; will sink g/cm³, a solubility: less than 0.1 mg/mL at 72.5 °F (NTP, 1992). It is also known as Bromoform and tribromomethane.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Bromoform
Property Insights of Bromoform
The XLogP value of 2.8 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Bromoform. With a topological polar surface area (TPSA) of 0.0 Ų, Bromoform exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Bromoform has 0 hydrogen bond donor(s) and 0 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Bromoform?
The CAS number of Bromoform is 75-25-2.
What is the molecular formula of Bromoform?
The molecular formula of Bromoform is CHBr3.
What is the molecular weight of Bromoform?
The molecular weight of Bromoform is 249.76283 g/mol.
What are the applications of Bromoform?
Bromoform is used in heterocycle construction in medicinal chemistry and agrochemical discovery, as well as pharmaceutical synthesis routes and API production. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies Bromoform (CAS 75-25-2) with custom synthesis...
Where can I buy Bromoform?
You can request a quote for Bromoform directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Bromoform?
Yes, CoreyChem provides custom synthesis services for Bromoform and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.