Dichlorofluoromethane
TL;DR: Dichlorofluoromethane (CAS 75-43-4) is a chemical compound with molecular formula CHCl2F and molecular weight 101.94393 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
dichloro(fluoro)methane
Also Known As: Dichlorofluoromethane, Fluorodichloromethane, Algofrene type 5, dichloro(fluoro)methane, Arcton 7
Application Areas
Top 5 of 22 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | CHCl2F |
| Molecular Weight | 101.94393 g/mol |
| XLogP | 2.0 |
| Topological Polar Surface Area (TPSA) | 0.0 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 1 |
| Rotatable Bonds | 0 |
| Exact Mass | 101.94393 Da |
| Heavy Atoms | 4 |
| Complexity | 13.0 |
| Melting Point | -211 °F (USCG, 1999) |
| Boiling Point | 48 °F at 760 mmHg (USCG, 1999) |
| Density | 1.48 at 68 °F (USCG, 1999) - Denser than water; will sink |
| Vapor Pressure | 2217.93 mmHg (USCG, 1999) |
| Refractive Index | Index of refraction: 1.3724 @ 9 °C/D |
| Solubility | 0.7 % at 86 °F (NIOSH, 2024) |
| SMILES | C(F)(Cl)Cl |
| InChIKey | UMNKXPULIDJLSU-UHFFFAOYSA-N |
Product Description
Applications: Dichlorofluoromethane is used in heterocycle construction in medicinal chemistry and agrochemical discovery, as well as pharmaceutical synthesis routes and API production. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
Dichlorofluoromethane is a heterocyclic building block identified by CAS number 75-43-4 and the molecular formula CHCl2F and a molecular weight of 101.94 g/mol. Physically, the compound has a density of 1.48 at 68 °F (USCG, 1999) - Denser than water; will sink g/cm³, a solubility: 0.7 % at 86 °F (NIOSH, 2024). Synonyms include Dichlorofluoromethane and Fluorodichloromethane.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Dichlorofluoromethane
Property Insights of Dichlorofluoromethane
The XLogP value of 2.0 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Dichlorofluoromethane. With a topological polar surface area (TPSA) of 0.0 Ų, Dichlorofluoromethane exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Dichlorofluoromethane has 0 hydrogen bond donor(s) and 1 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Dichlorofluoromethane?
The CAS number of Dichlorofluoromethane is 75-43-4.
What is the molecular formula of Dichlorofluoromethane?
The molecular formula of Dichlorofluoromethane is CHCl2F.
What is the molecular weight of Dichlorofluoromethane?
The molecular weight of Dichlorofluoromethane is 101.94393 g/mol.
What are the applications of Dichlorofluoromethane?
Dichlorofluoromethane is used in heterocycle construction in medicinal chemistry and agrochemical discovery, as well as pharmaceutical synthesis routes and API production. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and...
Where can I buy Dichlorofluoromethane?
You can request a quote for Dichlorofluoromethane directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Dichlorofluoromethane?
Yes, CoreyChem provides custom synthesis services for Dichlorofluoromethane and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.