Amantadine
TL;DR: Amantadine (CAS 768-94-5) is a chemical compound with molecular formula C10H17N and molecular weight 151.1361 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
adamantan-1-amine
Also Known As: amantadine, 1-Adamantanamine, adamantan-1-amine, 1-Adamantylamine, 1-Aminoadamantane
Application Areas
Top 5 of 22 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C10H17N |
| Molecular Weight | 151.1361 g/mol |
| XLogP | 2.4 |
| Topological Polar Surface Area (TPSA) | 26.0 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 1 |
| Rotatable Bonds | 0 |
| Exact Mass | 151.1361 Da |
| Heavy Atoms | 11 |
| Complexity | 144.0 |
| Melting Point | 180-192 |
| Solubility | 6290 |
| SMILES | C1C2CC3CC1CC(C2)(C3)N |
| InChIKey | DKNWSYNQZKUICI-UHFFFAOYSA-N |
Product Description
Applications: Amantadine is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
A pharmaceutical intermediate supplied by CoreyChem, Amantadine (CAS 768-94-5) has the molecular formula C10H17N and a molecular weight of 151.14 g/mol. Reported properties include a solubility: 6290. Synonyms include amantadine and 1-Adamantanamine.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Amantadine
Property Insights of Amantadine
The XLogP value of 2.4 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Amantadine. With a topological polar surface area (TPSA) of 26.0 Ų, Amantadine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Amantadine has 1 hydrogen bond donor(s) and 1 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Amantadine?
The CAS number of Amantadine is 768-94-5.
What is the molecular formula of Amantadine?
The molecular formula of Amantadine is C10H17N.
What is the molecular weight of Amantadine?
The molecular weight of Amantadine is 151.1361 g/mol.
What are the applications of Amantadine?
Amantadine is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and...
Where can I buy Amantadine?
You can request a quote for Amantadine directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Amantadine?
Yes, CoreyChem provides custom synthesis services for Amantadine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.