Nizatidine
TL;DR: Nizatidine (CAS 76963-41-2) is a chemical compound with molecular formula C12H21N5O2S2 and molecular weight 331.11368 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
1-N'-[2-[[2-[(dimethylamino)methyl]-1,3-thiazol-4-yl]methylsulfanyl]ethyl]-1-N-methyl-2-nitroethene-1,1-diamine
Also Known As: nizatidine, Acinon, Axid, Nizatidina, Nizatidine-d3
Application Areas
Top 5 of 16 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C12H21N5O2S2 |
| Molecular Weight | 331.11368 g/mol |
| XLogP | 1.6 |
| Topological Polar Surface Area (TPSA) | 140.0 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 8 |
| Rotatable Bonds | 9 |
| Exact Mass | 331.11368 Da |
| Heavy Atoms | 21 |
| Complexity | 349.0 |
| Melting Point | 130-132 °C |
| Solubility | 10-33mg/mL |
| SMILES | CNC(=C[N+](=O)[O-])NCCSCC1=CSC(=N1)CN(C)C |
| InChIKey | SGXXNSQHWDMGGP-UHFFFAOYSA-N |
Product Description
Applications: Nizatidine is used in pharmaceutical synthesis routes and API production, as well as biotechnology workflows and life-science research. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
Nizatidine is a pharmaceutical intermediate identified by CAS number 76963-41-2 and the molecular formula C12H21N5O2S2 and a molecular weight of 331.11 g/mol. Physically, the compound has a solubility: 10-33mg/mL. Synonyms include nizatidine and Acinon.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Nizatidine
Property Insights of Nizatidine
The XLogP value of 1.6 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Nizatidine. The TPSA of 140.0 Ų indicates high polarity, suggesting Nizatidine may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Nizatidine has 2 hydrogen bond donor(s) and 8 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Nizatidine?
The CAS number of Nizatidine is 76963-41-2.
What is the molecular formula of Nizatidine?
The molecular formula of Nizatidine is C12H21N5O2S2.
What is the molecular weight of Nizatidine?
The molecular weight of Nizatidine is 331.11368 g/mol.
What are the applications of Nizatidine?
Nizatidine is used in pharmaceutical synthesis routes and API production, as well as biotechnology workflows and life-science research. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton...
Where can I buy Nizatidine?
You can request a quote for Nizatidine directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Nizatidine?
Yes, CoreyChem provides custom synthesis services for Nizatidine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.