Chlorthalidone
TL;DR: Chlorthalidone (CAS 77-36-1) is a chemical compound with molecular formula C14H11ClN2O4S and molecular weight 338.01282 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
2-chloro-5-(1-hydroxy-3-oxo-2H-isoindol-1-yl)benzenesulfonamide
Also Known As: chlorthalidone, Chlortalidone, Phthalamudine, Hygroton, Chlorphthalidolone
Application Areas
Top 5 of 16 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C14H11ClN2O4S |
| Molecular Weight | 338.01282 g/mol |
| XLogP | 0.9 |
| Topological Polar Surface Area (TPSA) | 118.0 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 2 |
| Exact Mass | 338.01282 Da |
| Heavy Atoms | 22 |
| Complexity | 564.0 |
| Melting Point | 239 |
| Solubility | 120 |
| SMILES | C1=CC=C2C(=C1)C(=O)NC2(C3=CC(=C(C=C3)Cl)S(=O)(=O)N)O |
| InChIKey | JIVPVXMEBJLZRO-UHFFFAOYSA-N |
Product Description
Applications: Chlorthalidone is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
Chlorthalidone is a pharmaceutical intermediate identified by CAS number 77-36-1 and the molecular formula C14H11ClN2O4S and a molecular weight of 338.01 g/mol. Physically, the compound has a solubility: 120. Synonyms include chlorthalidone and Chlortalidone.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Chlorthalidone
Property Insights of Chlorthalidone
The XLogP value of 0.9 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Chlorthalidone. The TPSA of 118.0 Ų falls within the moderate polarity range, balancing permeability and solubility for Chlorthalidone. Following Lipinski's Rule of Five, Chlorthalidone has 3 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Chlorthalidone?
The CAS number of Chlorthalidone is 77-36-1.
What is the molecular formula of Chlorthalidone?
The molecular formula of Chlorthalidone is C14H11ClN2O4S.
What is the molecular weight of Chlorthalidone?
The molecular weight of Chlorthalidone is 338.01282 g/mol.
What are the applications of Chlorthalidone?
Chlorthalidone is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and...
Where can I buy Chlorthalidone?
You can request a quote for Chlorthalidone directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Chlorthalidone?
Yes, CoreyChem provides custom synthesis services for Chlorthalidone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.