Dapsone
TL;DR: Dapsone (CAS 80-08-0) is a chemical compound with molecular formula C12H12N2O2S and molecular weight 248.06195 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
4-(4-aminophenyl)sulfonylaniline
Also Known As: dapsone, Diaphenylsulfone, Dapson, 4,4'-Sulfonyldianiline, Diphenasone
Application Areas
Top 5 of 22 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C12H12N2O2S |
| Molecular Weight | 248.06195 g/mol |
| XLogP | 1.0 |
| Topological Polar Surface Area (TPSA) | 94.6 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 2 |
| Exact Mass | 248.06195 Da |
| Heavy Atoms | 17 |
| Complexity | 306.0 |
| Melting Point | 347 to 349 °F (NTP, 1992) |
| Density | 1.33 at 77 °F (NTP, 1992) - Denser than water; will sink |
| Flash Point | greater than 320 °F (NTP, 1992) |
| Vapor Pressure | 0.00000003 [mmHg] |
| Solubility | less than 1 mg/mL at 68 °F (NTP, 1992) |
| SMILES | C1=CC(=CC=C1N)S(=O)(=O)C2=CC=C(C=C2)N |
| InChIKey | MQJKPEGWNLWLTK-UHFFFAOYSA-N |
Product Description
Applications: Dapsone is used in polymer chemistry and functional materials synthesis, as well as pharmaceutical synthesis routes and API production. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
Dapsone (CAS 80-08-0) is a polymer intermediate with the molecular formula C12H12N2O2S and a molecular weight of 248.06 g/mol. Key physical properties include a density of 1.33 at 77 °F (NTP, 1992) - Denser than water; will sink g/cm³, a solubility: less than 1 mg/mL at 68 °F (NTP, 1992). Synonyms include dapsone and Diaphenylsulfone.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Dapsone
Property Insights of Dapsone
The XLogP value of 1.0 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Dapsone. The TPSA of 94.6 Ų falls within the moderate polarity range, balancing permeability and solubility for Dapsone. Following Lipinski's Rule of Five, Dapsone has 2 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Dapsone?
The CAS number of Dapsone is 80-08-0.
What is the molecular formula of Dapsone?
The molecular formula of Dapsone is C12H12N2O2S.
What is the molecular weight of Dapsone?
The molecular weight of Dapsone is 248.06195 g/mol.
What are the applications of Dapsone?
Dapsone is used in polymer chemistry and functional materials synthesis, as well as pharmaceutical synthesis routes and API production. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton...
Where can I buy Dapsone?
You can request a quote for Dapsone directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Dapsone?
Yes, CoreyChem provides custom synthesis services for Dapsone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.