Cyclizine
TL;DR: Cyclizine (CAS 82-92-8) is a chemical compound with molecular formula C18H22N2 and molecular weight 266.17828 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
1-benzhydryl-4-methylpiperazine
Also Known As: CYCLIZINE, Nautazine, Marezine, Ciclizina, Neo-devomit
Application Areas
Top 5 of 16 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C18H22N2 |
| Molecular Weight | 266.17828 g/mol |
| XLogP | 3.6 |
| Topological Polar Surface Area (TPSA) | 6.5 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 3 |
| Exact Mass | 266.17828 Da |
| Heavy Atoms | 20 |
| Complexity | 253.0 |
| Melting Point | 105.5-107.5 |
| Solubility | 1000 |
| SMILES | CN1CCN(CC1)C(C2=CC=CC=C2)C3=CC=CC=C3 |
| InChIKey | UVKZSORBKUEBAZ-UHFFFAOYSA-N |
Product Description
Applications: Cyclizine is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies Cyclizine (CAS 82-92-8) with custom synthesis available from milligram to multi-kilogram scale, supported by COA, MSDS, and HPLC/NMR/MS documentation.
A pharmaceutical intermediate supplied by CoreyChem, Cyclizine (CAS 82-92-8) has the molecular formula C18H22N2 and a molecular weight of 266.18 g/mol. Reported properties include a solubility: 1000. It is also known as CYCLIZINE and Nautazine.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Cyclizine
Property Insights of Cyclizine
The XLogP value of 3.6 indicates that Cyclizine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 6.5 Ų, Cyclizine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Cyclizine has 0 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Cyclizine?
The CAS number of Cyclizine is 82-92-8.
What is the molecular formula of Cyclizine?
The molecular formula of Cyclizine is C18H22N2.
What is the molecular weight of Cyclizine?
The molecular weight of Cyclizine is 266.17828 g/mol.
What are the applications of Cyclizine?
Cyclizine is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies Cyclizine (CAS 82-92-8) with custom synthesis...
Where can I buy Cyclizine?
You can request a quote for Cyclizine directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Cyclizine?
Yes, CoreyChem provides custom synthesis services for Cyclizine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.