Chlorcyclizine
TL;DR: Chlorcyclizine (CAS 82-93-9) is a chemical compound with molecular formula C18H21ClN2 and molecular weight 300.1393 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
1-[(4-chlorophenyl)-phenylmethyl]-4-methylpiperazine
Also Known As: chlorcyclizine, Chlorcycline, Alergicide, Perazyl, Chlorocycline
Application Areas
Top 5 of 13 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C18H21ClN2 |
| Molecular Weight | 300.1393 g/mol |
| XLogP | 4.5 |
| Topological Polar Surface Area (TPSA) | 6.5 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 3 |
| Exact Mass | 300.1393 Da |
| Heavy Atoms | 21 |
| Complexity | 300.0 |
| Melting Point | 216 |
| Boiling Point | 137-145 °C @ 0.1-0.15 MM HG |
| Flash Point | No Data |
| Solubility | 1 G SOL IN ABOUT 2 ML H2O, 11 ML ALC; 1 G SOL IN ABOUT 4 ML CHLOROFORM; PRACTICALLY INSOL IN ETHER, BENZENE /CHLORCYCLIZINE HYDROCHLORIDE/ |
| SMILES | CN1CCN(CC1)C(C2=CC=CC=C2)C3=CC=C(C=C3)Cl |
| InChIKey | WFNAKBGANONZEQ-UHFFFAOYSA-N |
Product Description
Applications: Chlorcyclizine is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies Chlorcyclizine (CAS 82-93-9) with custom synthesis available from milligram to multi-kilogram scale, supported by COA, MSDS, and HPLC/NMR/MS documentation.
Chlorcyclizine is a pharmaceutical intermediate identified by CAS number 82-93-9 and the molecular formula C18H21ClN2 and a molecular weight of 300.14 g/mol. Physically, the compound has a solubility: 1 G SOL IN ABOUT 2 ML H2O, 11 ML ALC; 1 G SOL IN ABOUT 4 ML CHLOROFORM; PRACTICALLY INSOL IN ETHER, BENZENE /CHLORCYCLIZINE HYDROCHLORIDE/. It is also known as chlorcyclizine and Chlorcycline.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Chlorcyclizine
Property Insights of Chlorcyclizine
The XLogP value of 4.5 indicates that Chlorcyclizine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 6.5 Ų, Chlorcyclizine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Chlorcyclizine has 0 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Chlorcyclizine?
The CAS number of Chlorcyclizine is 82-93-9.
What is the molecular formula of Chlorcyclizine?
The molecular formula of Chlorcyclizine is C18H21ClN2.
What is the molecular weight of Chlorcyclizine?
The molecular weight of Chlorcyclizine is 300.1393 g/mol.
What are the applications of Chlorcyclizine?
Chlorcyclizine is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies Chlorcyclizine (CAS 82-93-9) with custom...
Where can I buy Chlorcyclizine?
You can request a quote for Chlorcyclizine directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Chlorcyclizine?
Yes, CoreyChem provides custom synthesis services for Chlorcyclizine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.