Naphazoline
TL;DR: Naphazoline (CAS 835-31-4) is a chemical compound with molecular formula C14H14N2 and molecular weight 210.11569 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
2-(naphthalen-1-ylmethyl)-4,5-dihydro-1H-imidazole
Also Known As: naphazoline, Naphthizine, Nafazolina, Nafazolin, Clearine
Application Areas
Top 5 of 13 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C14H14N2 |
| Molecular Weight | 210.11569 g/mol |
| XLogP | 2.1 |
| Topological Polar Surface Area (TPSA) | 24.4 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 1 |
| Rotatable Bonds | 2 |
| Exact Mass | 210.11569 Da |
| Heavy Atoms | 16 |
| Complexity | 272.0 |
| Boiling Point | 440.466 |
| SMILES | C1CN=C(N1)CC2=CC=CC3=CC=CC=C32 |
| InChIKey | CNIIGCLFLJGOGP-UHFFFAOYSA-N |
Product Description
Applications: Naphazoline is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
Naphazoline is a pharmaceutical intermediate identified by CAS number 835-31-4 and the molecular formula C14H14N2 and a molecular weight of 210.12 g/mol. Synonyms include naphazoline and Naphthizine.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Naphazoline
Property Insights of Naphazoline
The XLogP value of 2.1 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Naphazoline. With a topological polar surface area (TPSA) of 24.4 Ų, Naphazoline exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Naphazoline has 1 hydrogen bond donor(s) and 1 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Naphazoline?
The CAS number of Naphazoline is 835-31-4.
What is the molecular formula of Naphazoline?
The molecular formula of Naphazoline is C14H14N2.
What is the molecular weight of Naphazoline?
The molecular weight of Naphazoline is 210.11569 g/mol.
What are the applications of Naphazoline?
Naphazoline is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and...
Where can I buy Naphazoline?
You can request a quote for Naphazoline directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Naphazoline?
Yes, CoreyChem provides custom synthesis services for Naphazoline and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.