Norfluoxetine
TL;DR: Norfluoxetine (CAS 83891-03-6) is a chemical compound with molecular formula C16H16F3NO and molecular weight 295.1184 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine
Also Known As: Norfluoxetine, Desmethylfluoxetine, Norfluoxetin, (S)-Norfluoxetine, Seproxetine HCl
Application Areas
Top 5 of 5 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C16H16F3NO |
| Molecular Weight | 295.1184 g/mol |
| XLogP | 3.5 |
| Topological Polar Surface Area (TPSA) | 35.3 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 5 |
| Exact Mass | 295.1184 Da |
| Heavy Atoms | 21 |
| Complexity | 294.0 |
| SMILES | C1=CC=C(C=C1)C(CCN)OC2=CC=C(C=C2)C(F)(F)F |
| InChIKey | WIQRCHMSJFFONW-UHFFFAOYSA-N |
Chemical Property Profile of Norfluoxetine
Property Insights of Norfluoxetine
The XLogP value of 3.5 indicates that Norfluoxetine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 35.3 Ų, Norfluoxetine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Norfluoxetine has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Norfluoxetine?
The CAS number of Norfluoxetine is 83891-03-6.
What is the molecular formula of Norfluoxetine?
The molecular formula of Norfluoxetine is C16H16F3NO.
What is the molecular weight of Norfluoxetine?
The molecular weight of Norfluoxetine is 295.1184 g/mol.
Where can I buy Norfluoxetine?
You can request a quote for Norfluoxetine directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Norfluoxetine?
Yes, CoreyChem provides custom synthesis services for Norfluoxetine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.