Biphalin

(2S)-2-amino-N-[(2R)-1-[[2-[[(2S)-1-[2-[(2S)-2-[[2-[[(2R)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]propanoyl]amino]acetyl]amino]-3-phenylpropanoyl]hydrazinyl]-1-oxo-3-phenylpropan-2-yl]amino]-2-oxoethyl]amino]-1-oxopropan-2-yl]-3-(4-hydroxyphenyl)propanamide

Also Known As: Biphalin|enkephalin dimer|D-Enk-O|Dala(2)|D-ENK|(Tyr-ala-gly-phe-NH2)2|Bis(tyr-ala-gly-phenh2)hydrazide|Biphalin trifluoroacetate salt (|(Tyrosyl-alanyl-glycyl-phenylalaninamide)dimer|Bis(tyrosyl-alanyl-glycyl-phenylalaninamide)hydrazide|1,2-Bis(L-Tyr-D-Ala-Gly-L-Phe-)hydrazine|H-Tyr-D-Ala-Gly-Phe-NH)2 trifluoroacetate salt|(2S)-2-amino-N-[(2R)-1-[[2-[[(2S)-1-[2-[(2S)-2-[[2-[[(2R)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]propanoyl]amino]acetyl]amino]-3-phenylpropanoyl]hydrazinyl]-1-oxo-3-phenylpropan-2-yl]amino]-2-oxoethyl]amino]-1-oxopropan-2-yl]-3-(4-hydroxyphenyl)propanamide|(2S)-2-AMINO-N-[(1R)-1-[({[(1S)-1-{N'-[(2S)-2-{2-[(2R)-2-[(2S)-2-AMINO-3-(4-HYDROXYPHENYL)PROPANAMIDO]PROPANAMIDO]ACETAMIDO}-3-PHENYLPROPANOYL]HYDRAZINECARBONYL}-2-PHENYLETHYL]CARBAMOYL}METHYL)CARBAMOYL]ETHYL]-3-(4-HYDROXYPHENYL)PROPANAMIDE|(2S,2'S)-N,N'-((2R,8S,13S,19R)-8,13-dibenzyl-3,6,9,12,15,18-hexaoxo-4,7,10,11,14,17-hexaazaicosane-2,19-diyl)bis(2-amino-3-(4-hydroxyphenyl)propanamide)|L-Phenylalanine, N-(N-(N-L-tyrosyl-D-alanyl)glycyl)-, 2-(N-(N-(N-L-tyrosyl-D-alanyl)glycyl)-L-phenylalanyl)hydrazide|(2R,2'R)-N,N'-(Hydrazine-1,2-diylbis{[(2S)-1-oxo-3-phenylpropane-1,2-diyl]azanediyl(2-oxoethane-2,1-diyl)})bis{2-[(2S)-2-amino-3-(4-hydroxyphenyl)propanamido]propanamide}|(2S)-2-amino-N-[(1R)-1-[({[(1S)-1-{N''-[(2S)-2-{2-[(2R)-2-[(2S)-2-amino-3-(4-hydroxyphenyl)propanamido]propanamido]acetamido}-3-phenylpropanoyl]hydrazinecarbonyl}-2-phenylethyl]carbamoyl}methyl)carbamoyl]ethyl]-3-(4-hydroxyphenyl)propanamide|(2S,2'S)-N,N'-[(2R,8S,13S,19R)-8,13-Dibenzyl-3,6,9,12,15,18-hexao xo-4,7,10,11,14,17-hexaazaicosane-2,19-diyl]bis[2-amino-3-(4-hydr oxyphenyl)propanamide] (non-preferred name)|1-Naphthalenecarboxylic acid, decahydro-5-[(3R)-3-hydroxy-3-methyl-4-pentenyl]-1,4a-dimethyl-6-methylene-, (1R,4aR,5S,8aR)-|L-Phenylalanine, L-tyrosyl-D-alanylglycyl-, 2-(L-tyrosyl-D-alanylglycyl-L-phenylalanyl)hydrazide|L-Phenylalanine, N-[N-(N-L-tyrosyl-D-alanyl)glycyl]-, 2-[N-[N-(N-L-tyrosyl-D-alanyl)glycyl]-L-phenylalanyl]hydrazide

Molecular Formula	C46H56N10O10
Molecular Weight	908.4181 g/mol
LogP	-1.6182
Topological Polar Surface Area	325.3 Ų
Hydrogen Bond Donors	12
Hydrogen Bond Acceptors	12
Rotatable Bonds	22
Exact Mass	908.4181
Monoisotopic Mass	908.4181
Heavy Atoms	66
Complexity	2121.993

Chemical Identifiers

CAS Number	83916-01-2
SMILES	C[C@H](C(=O)NCC(=O)N[C@@H](CC1=CC=CC=C1)C(=O)NNC(=O)[C@H](CC2=CC=CC=C2)NC(=O)CNC(=O)[C@@H](C)NC(=O)[C@H](CC3=CC=C(C=C3)O)N)NC(=O)[C@H](CC4=CC=C(C=C4)O)N