Thiopropazate
TL;DR: Thiopropazate (CAS 84-06-0) is a chemical compound with molecular formula C23H28ClN3O2S and molecular weight 445.1591 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
2-[4-[3-(2-chlorophenothiazin-10-yl)propyl]piperazin-1-yl]ethyl acetate
Also Known As: THIOPROPAZATE, Thiopropazat, Dartalan, Tiopropazato, Dartal
Application Areas
Top 5 of 10 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C23H28ClN3O2S |
| Molecular Weight | 445.1591 g/mol |
| XLogP | 4.8 |
| Topological Polar Surface Area (TPSA) | 61.3 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 8 |
| Exact Mass | 445.1591 Da |
| Heavy Atoms | 30 |
| Complexity | 561.0 |
| Melting Point | MP: 167-169 °C /DIMALEATE/ |
| Boiling Point | 214-218 °C @ 0.1 MM HG |
| Refractive Index | INDEX OF REFRACTION: 1.589 (ALPHA), 1.609 (BETA), 1.700 (GAMMA) /DIHYDROCHLORIDE/ |
| Solubility | SOL IN ETHER |
| SMILES | CC(=O)OCCN1CCN(CC1)CCCN2C3=CC=CC=C3SC4=C2C=C(C=C4)Cl |
| InChIKey | AIUHRQHVWSUTGJ-UHFFFAOYSA-N |
Product Description
Applications: Thiopropazate is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies Thiopropazate (CAS 84-06-0) with custom synthesis available from milligram to multi-kilogram scale, supported by COA, MSDS, and HPLC/NMR/MS documentation.
A pharmaceutical intermediate supplied by CoreyChem, Thiopropazate (CAS 84-06-0) has the molecular formula C23H28ClN3O2S and a molecular weight of 445.16 g/mol. Reported properties include a solubility: SOL IN ETHER. It is also known as THIOPROPAZATE and Thiopropazat.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Thiopropazate
Property Insights of Thiopropazate
The XLogP value of 4.8 indicates that Thiopropazate is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 61.3 Ų falls within the moderate polarity range, balancing permeability and solubility for Thiopropazate. Following Lipinski's Rule of Five, Thiopropazate has 0 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Thiopropazate?
The CAS number of Thiopropazate is 84-06-0.
What is the molecular formula of Thiopropazate?
The molecular formula of Thiopropazate is C23H28ClN3O2S.
What is the molecular weight of Thiopropazate?
The molecular weight of Thiopropazate is 445.1591 g/mol.
What are the applications of Thiopropazate?
Thiopropazate is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies Thiopropazate (CAS 84-06-0) with custom...
Where can I buy Thiopropazate?
You can request a quote for Thiopropazate directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Thiopropazate?
Yes, CoreyChem provides custom synthesis services for Thiopropazate and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.