1-(5-Isoquinolinylsulfonyl)piperazine
TL;DR: 1-(5-Isoquinolinylsulfonyl)piperazine (CAS 84468-24-6) is a chemical compound with molecular formula C13H15N3O2S and molecular weight 277.0885 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
5-piperazin-1-ylsulfonylisoquinoline
Also Known As: 5-(piperazin-1-ylsulfonyl)isoquinoline, 1-(5-Isoquinolinesulfonyl)piperazine, HA 100 (pharmaceutical), IQSP, C-I-QP
Application Areas
Top 5 of 5 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C13H15N3O2S |
| Molecular Weight | 277.0885 g/mol |
| XLogP | 0.6 |
| Topological Polar Surface Area (TPSA) | 70.7 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 2 |
| Exact Mass | 277.0885 Da |
| Heavy Atoms | 19 |
| Complexity | 401.0 |
| SMILES | C1CN(CCN1)S(=O)(=O)C2=CC=CC3=C2C=CN=C3 |
| InChIKey | UPTYCYWTFGTCCG-UHFFFAOYSA-N |
Product Description
Applications: 1-(5-Isoquinolinylsulfonyl)piperazine is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies 1-(5-Isoquinolinylsulfonyl)piperazine (CAS 84468-24-6) with custom synthesis available from milligram to multi-kilogram scale, supported by COA, MSDS, and HPLC/NMR/MS documentation.
1-(5-Isoquinolinylsulfonyl)piperazine (CAS 84468-24-6) is a pharmaceutical intermediate with the molecular formula C13H15N3O2S and a molecular weight of 277.09 g/mol. It is also known as ha-100 and 5-(piperazin-1-ylsulfonyl)isoquinoline.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of 1-(5-Isoquinolinylsulfonyl)piperazine
Property Insights of 1-(5-Isoquinolinylsulfonyl)piperazine
The XLogP value of 0.6 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 1-(5-Isoquinolinylsulfonyl)piperazine. The TPSA of 70.7 Ų falls within the moderate polarity range, balancing permeability and solubility for 1-(5-Isoquinolinylsulfonyl)piperazine. Following Lipinski's Rule of Five, 1-(5-Isoquinolinylsulfonyl)piperazine has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of 1-(5-Isoquinolinylsulfonyl)piperazine?
The CAS number of 1-(5-Isoquinolinylsulfonyl)piperazine is 84468-24-6.
What is the molecular formula of 1-(5-Isoquinolinylsulfonyl)piperazine?
The molecular formula of 1-(5-Isoquinolinylsulfonyl)piperazine is C13H15N3O2S.
What is the molecular weight of 1-(5-Isoquinolinylsulfonyl)piperazine?
The molecular weight of 1-(5-Isoquinolinylsulfonyl)piperazine is 277.0885 g/mol.
What are the applications of 1-(5-Isoquinolinylsulfonyl)piperazine?
1-(5-Isoquinolinylsulfonyl)piperazine is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies...
Where can I buy 1-(5-Isoquinolinylsulfonyl)piperazine?
You can request a quote for 1-(5-Isoquinolinylsulfonyl)piperazine directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 1-(5-Isoquinolinylsulfonyl)piperazine?
Yes, CoreyChem provides custom synthesis services for 1-(5-Isoquinolinylsulfonyl)piperazine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.