1-(5-Isoquinolinylsulfonyl)-2-Methylpiperazine
TL;DR: 1-(5-Isoquinolinylsulfonyl)-2-Methylpiperazine (CAS 84477-87-2) is a chemical compound with molecular formula C14H17N3O2S and molecular weight 291.10416 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
5-(2-methylpiperazin-1-yl)sulfonylisoquinoline
Also Known As: Protein kinase inhibitor H-7, Isoquinoline deriv., H-7 dihydrochloride, H-7 inhibitor, 1-(5-ISOQUINOLINESULFONYL)-2-METHYLPIPERAZINE
Application Areas
Top 5 of 7 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C14H17N3O2S |
| Molecular Weight | 291.10416 g/mol |
| XLogP | 1.0 |
| Topological Polar Surface Area (TPSA) | 70.7 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 2 |
| Exact Mass | 291.10416 Da |
| Heavy Atoms | 20 |
| Complexity | 434.0 |
| SMILES | CC1CNCCN1S(=O)(=O)C2=CC=CC3=C2C=CN=C3 |
| InChIKey | BDVFVCGFMNCYPV-UHFFFAOYSA-N |
Product Description
Applications: 1-(5-Isoquinolinylsulfonyl)-2-Methylpiperazine is used in pharmaceutical synthesis routes and API production, as well as biotechnology workflows and life-science research. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
A pharmaceutical intermediate supplied by CoreyChem, 1-(5-Isoquinolinylsulfonyl)-2-Methylpiperazine (CAS 84477-87-2) has the molecular formula C14H17N3O2S and a molecular weight of 291.1 g/mol. Synonyms include Protein kinase inhibitor H-7 and Isoquinoline deriv..
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of 1-(5-Isoquinolinylsulfonyl)-2-Methylpiperazine
Property Insights of 1-(5-Isoquinolinylsulfonyl)-2-Methylpiperazine
The XLogP value of 1.0 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 1-(5-Isoquinolinylsulfonyl)-2-Methylpiperazine. The TPSA of 70.7 Ų falls within the moderate polarity range, balancing permeability and solubility for 1-(5-Isoquinolinylsulfonyl)-2-Methylpiperazine. Following Lipinski's Rule of Five, 1-(5-Isoquinolinylsulfonyl)-2-Methylpiperazine has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of 1-(5-Isoquinolinylsulfonyl)-2-Methylpiperazine?
The CAS number of 1-(5-Isoquinolinylsulfonyl)-2-Methylpiperazine is 84477-87-2.
What is the molecular formula of 1-(5-Isoquinolinylsulfonyl)-2-Methylpiperazine?
The molecular formula of 1-(5-Isoquinolinylsulfonyl)-2-Methylpiperazine is C14H17N3O2S.
What is the molecular weight of 1-(5-Isoquinolinylsulfonyl)-2-Methylpiperazine?
The molecular weight of 1-(5-Isoquinolinylsulfonyl)-2-Methylpiperazine is 291.10416 g/mol.
What are the applications of 1-(5-Isoquinolinylsulfonyl)-2-Methylpiperazine?
1-(5-Isoquinolinylsulfonyl)-2-Methylpiperazine is used in pharmaceutical synthesis routes and API production, as well as biotechnology workflows and life-science research. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and...
Where can I buy 1-(5-Isoquinolinylsulfonyl)-2-Methylpiperazine?
You can request a quote for 1-(5-Isoquinolinylsulfonyl)-2-Methylpiperazine directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 1-(5-Isoquinolinylsulfonyl)-2-Methylpiperazine?
Yes, CoreyChem provides custom synthesis services for 1-(5-Isoquinolinylsulfonyl)-2-Methylpiperazine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.