Avermectin A1a, 5-O-demethyl-26-hydroxy- structure

Avermectin A1a, 5-O-demethyl-26-hydroxy-

(1'R,2R,3S,4'S,6S,8'R,10'E,12'S,13'S,14'E,16'E,20'R,21'R,24'S)-2-[(2S)-butan-2-yl]-21',24'-dihydroxy-12'-[(2R,4S,5S,6S)-5-[(2S,4S,5S,6S)-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy-4-methoxy-6-methyloxan-2-yl]oxy-22'-(hydroxymethyl)-3,11',13'-trimethylspiro[2,3-dihydropyran-6,6'-3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene]-2'-one

Also Known As: 4a-Hydroxyavermectin B1|4a-HydroxyavermectinB1|5-O-Demethyl-26-hydroxyavermectin A1a|Avermectin A1a, 5-O-demethyl-26-hydroxy-

CAS: 86629-72-3
Molecular Formula C48H72O15
Molecular Weight 888.4871 g/mol
LogP 4.3498
Topological Polar Surface Area 190.29 Ų
Hydrogen Bond Donors 4
Hydrogen Bond Acceptors 15
Rotatable Bonds 9
Exact Mass 888.4871
Monoisotopic Mass 888.4871
Heavy Atoms 63
Complexity 1744.5277

Chemical Identifiers

CAS Number 86629-72-3
SMILES CC[C@H](C)[C@@H]1[C@H](C=C[C@@]2(O1)C[C@@H]3C[C@H](O2)C/C=C(/[C@H]([C@H](/C=C/C=C/4\CO[C@H]5[C@@]4([C@@H](C=C([C@H]5O)CO)C(=O)O3)O)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O[C@H]7C[C@@H]([C@H]([C@@H](O7)C)O)OC)OC)\C)C

Product Overview

Avermectin A1a, 5-O-demethyl-26-hydroxy- (CAS 86629-72-3), with molecular formula C48H72O15 and molecular weight 888.4871 g/mol. IUPAC: (1'R,2R,3S,4'S,6S,8'R,10'E,12'S,13'S,14'E,16'E,20'R,21'R,24'S)-2-[(2S)-butan-2-yl]-21',24'-dihydroxy-12'-[(2R,4S,5S,6S)-5-[(2S,4S,5S,6S)-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy-4-methoxy-6-methyloxan-2-yl]oxy-22'-(hydroxymethyl)-3,11',13'-trimethylspiro[2,3-dihydropyran-6,6'-3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene]-2'-one.

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