10-Aminocamptothecin
TL;DR: 10-Aminocamptothecin (CAS 86639-63-6) is a chemical compound with molecular formula C20H17N3O4 and molecular weight 363.12192 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
(19S)-7-amino-19-ethyl-19-hydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2(11),3,5,7,9,15(20)-heptaene-14,18-dione
Also Known As: 10-Aminocamptothecin, Camptothecin, 10-amino-, 10-Amino-cpt, 9-Amino-cpt, 9-Aminocamptothecin
Application Areas
Top 5 of 5 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C20H17N3O4 |
| Molecular Weight | 363.12192 g/mol |
| XLogP | 0.3 |
| Topological Polar Surface Area (TPSA) | 106.0 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 1 |
| Exact Mass | 363.12192 Da |
| Heavy Atoms | 27 |
| Complexity | 775.0 |
| SMILES | CC[C@@]1(C2=C(COC1=O)C(=O)N3CC4=C(C3=C2)N=C5C=CC(=CC5=C4)N)O |
| InChIKey | MVUUMBZAHAKPKQ-FQEVSTJZSA-N |
Chemical Property Profile of 10-Aminocamptothecin
Property Insights of 10-Aminocamptothecin
The XLogP value of 0.3 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 10-Aminocamptothecin. The TPSA of 106.0 Ų falls within the moderate polarity range, balancing permeability and solubility for 10-Aminocamptothecin. Following Lipinski's Rule of Five, 10-Aminocamptothecin has 2 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of 10-Aminocamptothecin?
The CAS number of 10-Aminocamptothecin is 86639-63-6.
What is the molecular formula of 10-Aminocamptothecin?
The molecular formula of 10-Aminocamptothecin is C20H17N3O4.
What is the molecular weight of 10-Aminocamptothecin?
The molecular weight of 10-Aminocamptothecin is 363.12192 g/mol.
Where can I buy 10-Aminocamptothecin?
You can request a quote for 10-Aminocamptothecin directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 10-Aminocamptothecin?
Yes, CoreyChem provides custom synthesis services for 10-Aminocamptothecin and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.