Lonapalene
TL;DR: Lonapalene (CAS 91431-42-4) is a chemical compound with molecular formula C16H15ClO6 and molecular weight 338.05573 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
(4-acetyloxy-6-chloro-2,3-dimethoxynaphthalen-1-yl) acetate
Also Known As: Lonapaleno, Lonapalenum, methotrexate, Lonapalenum [Latin], Lonapaleno [Spanish]
Application Areas
Top 5 of 9 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C16H15ClO6 |
| Molecular Weight | 338.05573 g/mol |
| XLogP | 3.2 |
| Topological Polar Surface Area (TPSA) | 71.1 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 6 |
| Exact Mass | 338.05573 Da |
| Heavy Atoms | 23 |
| Complexity | 442.0 |
| SMILES | CC(=O)OC1=C(C(=C(C2=C1C=CC(=C2)Cl)OC(=O)C)OC)OC |
| InChIKey | IFWMVQUGSGWCRP-UHFFFAOYSA-N |
Chemical Property Profile of Lonapalene
Property Insights of Lonapalene
The XLogP value of 3.2 indicates that Lonapalene is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 71.1 Ų falls within the moderate polarity range, balancing permeability and solubility for Lonapalene. Following Lipinski's Rule of Five, Lonapalene has 0 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Lonapalene?
The CAS number of Lonapalene is 91431-42-4.
What is the molecular formula of Lonapalene?
The molecular formula of Lonapalene is C16H15ClO6.
What is the molecular weight of Lonapalene?
The molecular weight of Lonapalene is 338.05573 g/mol.
Where can I buy Lonapalene?
You can request a quote for Lonapalene directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Lonapalene?
Yes, CoreyChem provides custom synthesis services for Lonapalene and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.