Thioglycerol
TL;DR: Thioglycerol (CAS 96-27-5) is a chemical compound with molecular formula C3H8O2S and molecular weight 108.0245 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
3-sulfanylpropane-1,2-diol
Also Known As: 1-Thioglycerol, Monothioglycerol, 3-Mercapto-1,2-propanediol, Thioglycerin, THIOGLYCEROL
Application Areas
Top 5 of 22 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C3H8O2S |
| Molecular Weight | 108.0245 g/mol |
| XLogP | -0.8 |
| Topological Polar Surface Area (TPSA) | 41.5 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 2 |
| Exact Mass | 108.0245 Da |
| Heavy Atoms | 6 |
| Complexity | 32.0 |
| Boiling Point | 118 °C @ 5 MM HG |
| Density | 1.295 |
| Refractive Index | INDEX OF REFRACTION BETWEEN 1.521 & 1.526; PH (1 IN 10 SOLN) BETWEEN 3.5 & 7 |
| Solubility | SLIGHTLY SOL IN WATER; MISCIBLE WITH ALCOHOL; INSOL IN ETHER |
| SMILES | C(C(CS)O)O |
| InChIKey | PJUIMOJAAPLTRJ-UHFFFAOYSA-N |
Product Description
Applications: Thioglycerol is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
A pharmaceutical intermediate supplied by CoreyChem, Thioglycerol (CAS 96-27-5) has the molecular formula C3H8O2S and a molecular weight of 108.02 g/mol. Reported properties include a density of 1.295 g/cm³, a solubility: SLIGHTLY SOL IN WATER; MISCIBLE WITH ALCOHOL; INSOL IN ETHER. Synonyms include 1-Thioglycerol and Monothioglycerol.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Thioglycerol
Property Insights of Thioglycerol
The XLogP value of -0.8 indicates that Thioglycerol is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. With a topological polar surface area (TPSA) of 41.5 Ų, Thioglycerol exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Thioglycerol has 3 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Thioglycerol?
The CAS number of Thioglycerol is 96-27-5.
What is the molecular formula of Thioglycerol?
The molecular formula of Thioglycerol is C3H8O2S.
What is the molecular weight of Thioglycerol?
The molecular weight of Thioglycerol is 108.0245 g/mol.
What are the applications of Thioglycerol?
Thioglycerol is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and...
Where can I buy Thioglycerol?
You can request a quote for Thioglycerol directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Thioglycerol?
Yes, CoreyChem provides custom synthesis services for Thioglycerol and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.