2-Chlorothiophene
TL;DR: 2-Chlorothiophene (CAS 96-43-5) is a chemical compound with molecular formula C4H3ClS and molecular weight 117.9644 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
2-chlorothiophene
Also Known As: 2-CHLOROTHIOPHENE, 2-Thienyl chloride, Thiophene, 2-chloro-, 2-chlorthiophen, chlorothiophene
Application Areas
Top 5 of 19 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C4H3ClS |
| Molecular Weight | 117.9644 g/mol |
| XLogP | 2.5 |
| Topological Polar Surface Area (TPSA) | 28.2 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 1 |
| Rotatable Bonds | 0 |
| Exact Mass | 117.9644 Da |
| Heavy Atoms | 6 |
| Complexity | 46.0 |
| SMILES | C1=CSC(=C1)Cl |
| InChIKey | GSFNQBFZFXUTBN-UHFFFAOYSA-N |
Product Description
Applications: 2-Chlorothiophene is used in heterocycle construction in medicinal chemistry and agrochemical discovery, as well as pharmaceutical synthesis routes and API production. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies 2-Chlorothiophene (CAS 96-43-5) with custom synthesis available from milligram to multi-kilogram scale, supported by COA, MSDS, and HPLC/NMR/MS documentation.
2-Chlorothiophene is a heterocyclic building block identified by CAS number 96-43-5 and the molecular formula C4H3ClS and a molecular weight of 117.96 g/mol. It is also known as 2-CHLOROTHIOPHENE and 2-Thienyl chloride.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of 2-Chlorothiophene
Property Insights of 2-Chlorothiophene
The XLogP value of 2.5 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 2-Chlorothiophene. With a topological polar surface area (TPSA) of 28.2 Ų, 2-Chlorothiophene exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 2-Chlorothiophene has 0 hydrogen bond donor(s) and 1 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of 2-Chlorothiophene?
The CAS number of 2-Chlorothiophene is 96-43-5.
What is the molecular formula of 2-Chlorothiophene?
The molecular formula of 2-Chlorothiophene is C4H3ClS.
What is the molecular weight of 2-Chlorothiophene?
The molecular weight of 2-Chlorothiophene is 117.9644 g/mol.
What are the applications of 2-Chlorothiophene?
2-Chlorothiophene is used in heterocycle construction in medicinal chemistry and agrochemical discovery, as well as pharmaceutical synthesis routes and API production. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies 2-Chlorothiophene (CAS 96-43-5) with...
Where can I buy 2-Chlorothiophene?
You can request a quote for 2-Chlorothiophene directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 2-Chlorothiophene?
Yes, CoreyChem provides custom synthesis services for 2-Chlorothiophene and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.