Troglitazone
TL;DR: Troglitazone (CAS 97322-87-7) is a chemical compound with molecular formula C24H27NO5S and molecular weight 441.16098 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
5-[[4-[(6-hydroxy-2,5,7,8-tetramethyl-3,4-dihydrochromen-2-yl)methoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione
Also Known As: troglitazone, Rezulin, Romglizone, Prelay, Romozin
Application Areas
Top 5 of 15 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C24H27NO5S |
| Molecular Weight | 441.16098 g/mol |
| XLogP | 5.1 |
| Topological Polar Surface Area (TPSA) | 110.0 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 5 |
| Exact Mass | 441.16098 Da |
| Heavy Atoms | 31 |
| Complexity | 681.0 |
| Melting Point | 184-186 °C |
| SMILES | CC1=C(C2=C(CCC(O2)(C)COC3=CC=C(C=C3)CC4C(=O)NC(=O)S4)C(=C1O)C)C |
| InChIKey | GXPHKUHSUJUWKP-UHFFFAOYSA-N |
Product Description
Applications: Troglitazone is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
Troglitazone (CAS 97322-87-7) is a pharmaceutical intermediate with the molecular formula C24H27NO5S and a molecular weight of 441.16 g/mol. Synonyms include troglitazone and Rezulin.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Troglitazone
Property Insights of Troglitazone
The XLogP value of 5.1 indicates that Troglitazone is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 110.0 Ų falls within the moderate polarity range, balancing permeability and solubility for Troglitazone. Following Lipinski's Rule of Five, Troglitazone has 2 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
What is the CAS number of Troglitazone?
The CAS number of Troglitazone is 97322-87-7.
What is the molecular formula of Troglitazone?
The molecular formula of Troglitazone is C24H27NO5S.
What is the molecular weight of Troglitazone?
The molecular weight of Troglitazone is 441.16098 g/mol.
What are the applications of Troglitazone?
Troglitazone is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and...
Where can I buy Troglitazone?
You can request a quote for Troglitazone directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Troglitazone?
Yes, CoreyChem provides custom synthesis services for Troglitazone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.