Nebivolol
TL;DR: Nebivolol (CAS 99200-09-6) is a chemical compound with molecular formula C22H25F2NO4 and molecular weight 405.17517 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
1-(6-fluoro-3,4-dihydro-2H-chromen-2-yl)-2-[[2-(6-fluoro-3,4-dihydro-2H-chromen-2-yl)-2-hydroxyethyl]amino]ethanol
Also Known As: Nebivolol, Bystolic, Nebilet, Levonebivolol, Nebivololum
Application Areas
Top 5 of 10 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C22H25F2NO4 |
| Molecular Weight | 405.17517 g/mol |
| XLogP | 3.0 |
| Topological Polar Surface Area (TPSA) | 71.0 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 6 |
| Exact Mass | 405.17517 Da |
| Heavy Atoms | 29 |
| Complexity | 483.0 |
| Melting Point | 223.0-228.0 |
| Solubility | 0.091g/100mL |
| SMILES | C1CC2=C(C=CC(=C2)F)OC1C(CNCC(C3CCC4=C(O3)C=CC(=C4)F)O)O |
| InChIKey | KOHIRBRYDXPAMZ-UHFFFAOYSA-N |
Chemical Property Profile of Nebivolol
Property Insights of Nebivolol
The XLogP value of 3.0 indicates that Nebivolol is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 71.0 Ų falls within the moderate polarity range, balancing permeability and solubility for Nebivolol. Following Lipinski's Rule of Five, Nebivolol has 3 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Nebivolol?
The CAS number of Nebivolol is 99200-09-6.
What is the molecular formula of Nebivolol?
The molecular formula of Nebivolol is C22H25F2NO4.
What is the molecular weight of Nebivolol?
The molecular weight of Nebivolol is 405.17517 g/mol.
Where can I buy Nebivolol?
You can request a quote for Nebivolol directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Nebivolol?
Yes, CoreyChem provides custom synthesis services for Nebivolol and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.