Uracil, 5-fluoro-N-((p-methoxyphenyl)sulfonyl)-

CAS Number: 105434-88-6

Formula: C11H9FN2O5SMW: 300.26 g/mol

Pharmaceutical Connection

Fluorouracil (5-FU) — Antimetabolite Chemotherapy Agent

Relationship: Sulfonyl Derivative

5-Fluoro-N-((p-methoxyphenyl)sulfonyl)uracil is a sulfonamide derivative of 5-Fluorouracil (5-FU), a cornerstone antimetabolite chemotherapy drug on the WHO Essential Medicines List. 5-FU and its derivatives are used in the treatment of colorectal, breast, stomach, and pancreatic cancers. The compound serves as a protected precursor or prodrug intermediate in fluoropyrimidine-based anticancer therapies.

Pharmaceutical Applications

Pharmaceutical research intermediate for fluoropyrimidine-based anticancer agents. Potential prodrug development for targeted 5-FU delivery with reduced systemic toxicity.

Regulatory & Quality Information

Related to FDA-approved 5-FU products. ICH Q3A guidelines apply for impurity profiling in pharmaceutical development.

Product Specifications

CAS Number: 105434-88-6
Chemical Name: Uracil, 5-fluoro-N-((p-methoxyphenyl)sulfonyl)-
Molecular Formula: C11H9FN2O5S
Molecular Weight: 300.26 g/mol

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