S-(+)-apomorphine

CAS Number: 39478-62-1

Formula: C17H17NO2MW: 267.32 g/mol

Pharmaceutical Connection

Apomorphine — Dopamine Agonist (Non-ergoline)

Relationship: Active Pharmaceutical Ingredient (S-enantiomer)

S-(+)-Apomorphine is the active S-enantiomer of Apomorphine, a non-ergoline dopamine agonist used in the treatment of Parkinson disease off-episodes and erectile dysfunction. Apomorphine hydrochloride (Apokyn) received FDA approval for acute, intermittent treatment of hypomobility "off" episodes in advanced Parkinson disease. The compound is derived from morphine but has no opioid activity - it is a potent D1/D2 dopamine receptor agonist.

Pharmaceutical Applications

Active pharmaceutical ingredient for Parkinson disease therapy. Research applications in dopamine receptor pharmacology. Reference standard for chiral purity analysis in apomorphine formulations.

Regulatory & Quality Information

FDA-approved as Apokyn (apomorphine hydrochloride injection). Controlled substance Schedule II. Manufactured under cGMP with strict stereochemical purity requirements.

Product Specifications

CAS Number: 39478-62-1
Chemical Name: S-(+)-apomorphine
Molecular Formula: C17H17NO2
Molecular Weight: 267.32 g/mol

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