1-Hydroxy-3-amino-2-pyrrolidone
TL;DR: 1-Hydroxy-3-amino-2-pyrrolidone (CAS 1003-51-6) is a chemical compound with molecular formula C4H8N2O2 and molecular weight 116.05858 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
3-amino-1-hydroxypyrrolidin-2-one
Also Known As: 3-amino-1-hydroxypyrrolidin-2-one, 3-Amino-1-hydroxy-pyrrolidin-2-one, 2-Pyrrolidinone, 3-amino-1-hydroxy-, 1-Hydroxy-3-amino-2-pyrrolidone, 3-Amino-1-hydroxy-2-pyrrolidinone
Application Areas
Top 5 of 9 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C4H8N2O2 |
| Molecular Weight | 116.05858 g/mol |
| XLogP | -1.5 |
| Topological Polar Surface Area (TPSA) | 66.6 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 0 |
| Exact Mass | 116.05858 Da |
| Heavy Atoms | 8 |
| Complexity | 115.0 |
| SMILES | C1CN(C(=O)C1N)O |
| InChIKey | HCKUBNLZMKAEIN-UHFFFAOYSA-N |
Product Description
Applications: 1-Hydroxy-3-amino-2-pyrrolidone is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
1-Hydroxy-3-amino-2-pyrrolidone (CAS 1003-51-6) is a pharmaceutical intermediate with the molecular formula C4H8N2O2 and a molecular weight of 116.06 g/mol. Synonyms include 3-amino-1-hydroxypyrrolidin-2-one and 3-Amino-1-hydroxy-pyrrolidin-2-one.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of 1-Hydroxy-3-amino-2-pyrrolidone
Property Insights of 1-Hydroxy-3-amino-2-pyrrolidone
The XLogP value of -1.5 indicates that 1-Hydroxy-3-amino-2-pyrrolidone is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 66.6 Ų falls within the moderate polarity range, balancing permeability and solubility for 1-Hydroxy-3-amino-2-pyrrolidone. Following Lipinski's Rule of Five, 1-Hydroxy-3-amino-2-pyrrolidone has 2 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of 1-Hydroxy-3-amino-2-pyrrolidone?
The CAS number of 1-Hydroxy-3-amino-2-pyrrolidone is 1003-51-6.
What is the molecular formula of 1-Hydroxy-3-amino-2-pyrrolidone?
The molecular formula of 1-Hydroxy-3-amino-2-pyrrolidone is C4H8N2O2.
What is the molecular weight of 1-Hydroxy-3-amino-2-pyrrolidone?
The molecular weight of 1-Hydroxy-3-amino-2-pyrrolidone is 116.05858 g/mol.
What are the applications of 1-Hydroxy-3-amino-2-pyrrolidone?
1-Hydroxy-3-amino-2-pyrrolidone is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog...
Where can I buy 1-Hydroxy-3-amino-2-pyrrolidone?
You can request a quote for 1-Hydroxy-3-amino-2-pyrrolidone directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 1-Hydroxy-3-amino-2-pyrrolidone?
Yes, CoreyChem provides custom synthesis services for 1-Hydroxy-3-amino-2-pyrrolidone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.