Acetaminophen
TL;DR: Acetaminophen (CAS 103-90-2) is a chemical compound with molecular formula C8H9NO2 and molecular weight 151.06332 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
N-(4-hydroxyphenyl)acetamide
Also Known As: acetaminophen, Paracetamol, 4-Acetamidophenol, Tylenol, Panadol
Application Areas
Top 5 of 22 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C8H9NO2 |
| Molecular Weight | 151.06332 g/mol |
| XLogP | 0.5 |
| Topological Polar Surface Area (TPSA) | 49.3 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 1 |
| Exact Mass | 151.06332 Da |
| Heavy Atoms | 11 |
| Complexity | 139.0 |
| Melting Point | 336 to 342 °F (NTP, 1992) |
| Boiling Point | >500 |
| Density | 1.293 at 70 °F (NTP, 1992) - Denser than water; will sink |
| Vapor Pressure | 0.000007 [mmHg] |
| Solubility | 1 to 5 mg/mL at 72 °F (NTP, 1992) |
| SMILES | CC(=O)NC1=CC=C(C=C1)O |
| InChIKey | RZVAJINKPMORJF-UHFFFAOYSA-N |
Product Description
Applications: Acetaminophen is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
Acetaminophen is a pharmaceutical intermediate identified by CAS number 103-90-2 and the molecular formula C8H9NO2 and a molecular weight of 151.06 g/mol. Physically, the compound has a density of 1.293 at 70 °F (NTP, 1992) - Denser than water; will sink g/cm³, a solubility: 1 to 5 mg/mL at 72 °F (NTP, 1992). Synonyms include acetaminophen and Paracetamol.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Acetaminophen
Property Insights of Acetaminophen
The XLogP value of 0.5 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Acetaminophen. With a topological polar surface area (TPSA) of 49.3 Ų, Acetaminophen exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Acetaminophen has 2 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Acetaminophen?
The CAS number of Acetaminophen is 103-90-2.
What is the molecular formula of Acetaminophen?
The molecular formula of Acetaminophen is C8H9NO2.
What is the molecular weight of Acetaminophen?
The molecular weight of Acetaminophen is 151.06332 g/mol.
What are the applications of Acetaminophen?
Acetaminophen is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and...
Where can I buy Acetaminophen?
You can request a quote for Acetaminophen directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Acetaminophen?
Yes, CoreyChem provides custom synthesis services for Acetaminophen and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.