Nppb
TL;DR: Nppb (CAS 107254-86-4) is a chemical compound with molecular formula C16H16N2O4 and molecular weight 300.111 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
5-nitro-2-(3-phenylpropylamino)benzoic acid
Also Known As: NPPB, 5-Nitro-2-(3-phenylpropylamino)benzoic acid, Compound 144, Hoechst 144, 5-nitro-2-[(3-phenylpropyl)amino]benzoic acid
Application Areas
Top 5 of 10 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C16H16N2O4 |
| Molecular Weight | 300.111 g/mol |
| XLogP | 4.1 |
| Topological Polar Surface Area (TPSA) | 95.2 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 6 |
| Exact Mass | 300.111 Da |
| Heavy Atoms | 22 |
| Complexity | 377.0 |
| Solubility | >45 [ug/mL] (The mean of the results at pH 7.4) |
| SMILES | C1=CC=C(C=C1)CCCNC2=C(C=C(C=C2)[N+](=O)[O-])C(=O)O |
| InChIKey | WBSMIPAMAXNXFS-UHFFFAOYSA-N |
Product Description
Applications: Nppb is used in pharmaceutical synthesis routes and API production, as well as biotechnology workflows and life-science research. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
Nppb (CAS 107254-86-4) is a pharmaceutical intermediate with the molecular formula C16H16N2O4 and a molecular weight of 300.11 g/mol. Key physical properties include a solubility: >45 [ug/mL] (The mean of the results at pH 7.4). Synonyms include NPPB and 5-Nitro-2-(3-phenylpropylamino)benzoic acid.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Nppb
Property Insights of Nppb
The XLogP value of 4.1 indicates that Nppb is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 95.2 Ų falls within the moderate polarity range, balancing permeability and solubility for Nppb. Following Lipinski's Rule of Five, Nppb has 2 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Nppb?
The CAS number of Nppb is 107254-86-4.
What is the molecular formula of Nppb?
The molecular formula of Nppb is C16H16N2O4.
What is the molecular weight of Nppb?
The molecular weight of Nppb is 300.111 g/mol.
What are the applications of Nppb?
Nppb is used in pharmaceutical synthesis routes and API production, as well as biotechnology workflows and life-science research. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale),...
Where can I buy Nppb?
You can request a quote for Nppb directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Nppb?
Yes, CoreyChem provides custom synthesis services for Nppb and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.