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HP 228 structure
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HP 228

TL;DR: HP 228 (CAS 109022-88-0) is a chemical compound with molecular formula C45H63N15O8 and molecular weight 941.4984 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.

(2S)-2-[[(2S)-2-aminohexanoyl]amino]-N-[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[(2-amino-2-oxoethyl)amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-(4H-imidazol-4-yl)-1-oxopropan-2-yl]pentanediamide

Also Known As: HP 228, (2S)-2-[[(2S)-2-aminohexanoyl]amino]-N-[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[(2-amino-2-oxoethyl)amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-(4H-imidazol-4-yl)-1-oxopropan-2-yl]pentanediamide, Acetyl-norleucyl-glutaminyl-histidyl-phenylalanyl-arginyl-tryptophyl-glycinamide, L-Norleucyl-L-glutaminyl-L-histidyl-L-phenylalanyl-L-arginyl-L-tryptophylglycinamide, (2S)-2-[[(2S)-2-Aminohexanoyl]amino]-N-[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[(2-amino-2-oxoethyl)amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]pentanediamide

CAS Number
109022-88-0
Molecular Formula
C45H63N15O8
Molecular Weight
941.4984 g/mol
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Technical Specifications

Molecular FormulaC45H63N15O8
Molecular Weight941.4984 g/mol
XLogP-1.6
Topological Polar Surface Area (TPSA)392.0 Ų
Hydrogen Bond Donors12
Hydrogen Bond Acceptors11
Rotatable Bonds29
Exact Mass941.4984 Da
Heavy Atoms68
Complexity1820.0
SMILESCCCC[C@@H](C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CC1C=NC=N1)C(=O)N[C@@H](CC2=CC=CC=C2)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CC3=CNC4=CC=CC=C43)C(=O)NCC(=O)N)N
InChIKeyJMWOGOGGXYCJQC-YYQZADIYSA-N

Product Description

Applications: HP 228 is used in organic synthesis and process chemistry. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies HP 228 (CAS 109022-88-0) with custom synthesis available from milligram to multi-kilogram scale, supported by COA, MSDS, and HPLC/NMR/MS documentation.

A fine chemical supplied by CoreyChem, HP 228 (CAS 109022-88-0) has the molecular formula C45H63N15O8 and a molecular weight of 941.5 g/mol. It is also known as HP 228 and Ac-Nle-gln-his-D-phe-arg-D-trp-gly-NH2.

Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.

Chemical Property Profile of HP 228

XLogP
-1.6
TPSA (Topological Polar Surface Area)
392.0
Hydrogen Bond Donors
12
Hydrogen Bond Acceptors
11
Rotatable Bonds
29
Heavy Atoms
68
Complexity
1820.0
Exact Mass
941.4984
Monoisotopic Mass
941.4984
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of HP 228

The XLogP value of -1.6 indicates that HP 228 is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 392.0 Ų indicates high polarity, suggesting HP 228 may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, HP 228 has 12 hydrogen bond donor(s) and 11 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the CAS number of HP 228?

The CAS number of HP 228 is 109022-88-0.

What is the molecular formula of HP 228?

The molecular formula of HP 228 is C45H63N15O8.

What is the molecular weight of HP 228?

The molecular weight of HP 228 is 941.4984 g/mol.

What are the applications of HP 228?

HP 228 is used in organic synthesis and process chemistry. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies HP 228 (CAS 109022-88-0) with custom synthesis available from milligram to multi-kilogram scale, supported by COA, MSDS, and HPLC/NMR/MS documentation.

Where can I buy HP 228?

You can request a quote for HP 228 directly from CoreyChem. Contact us or email [email protected] for pricing and availability.

Does CoreyChem offer custom synthesis for HP 228?

Yes, CoreyChem provides custom synthesis services for HP 228 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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