14-Hydroxyclarithromycin
TL;DR: 14-Hydroxyclarithromycin (CAS 110671-78-8) is a chemical compound with molecular formula C38H69NO14 and molecular weight 763.4718 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
(3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-12,13-dihydroxy-14-(1-hydroxyethyl)-4-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-7-methoxy-3,5,7,9,11,13-hexamethyl-oxacyclotetradecane-2,10-dione
Also Known As: 14-Hydroxyclarithromycin, 14-OH-Clarithromycin, 14-hydroxy-clarithromycin, Clarithromycin Impurity 43, 14-Hydroxy-6-0-methylerthromycin A
Technical Specifications
| Molecular Formula | C38H69NO14 |
| Molecular Weight | 763.4718 g/mol |
| XLogP | 2.6 |
| Topological Polar Surface Area (TPSA) | 203.0 Ų |
| Hydrogen Bond Donors | 5 |
| Hydrogen Bond Acceptors | 15 |
| Rotatable Bonds | 8 |
| Exact Mass | 763.4718 Da |
| Heavy Atoms | 53 |
| Complexity | 1230.0 |
| SMILES | C[C@@H]1C[C@@H]([C@H]([C@@H](O1)O[C@@H]2[C@H]([C@@H]([C@H](C(=O)O[C@@H]([C@@]([C@@H]([C@H](C(=O)[C@@H](C[C@@]2(C)OC)C)C)O)(C)O)C(C)O)C)O[C@H]3C[C@@]([C@H]([C@@H](O3)C)O)(C)OC)C)O)N(C)C |
| InChIKey | BLPFDXNVUDZBII-KNPZYKNQSA-N |
Chemical Property Profile of 14-Hydroxyclarithromycin
Property Insights of 14-Hydroxyclarithromycin
The XLogP value of 2.6 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 14-Hydroxyclarithromycin. The TPSA of 203.0 Ų indicates high polarity, suggesting 14-Hydroxyclarithromycin may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, 14-Hydroxyclarithromycin has 5 hydrogen bond donor(s) and 15 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
What is the CAS number of 14-Hydroxyclarithromycin?
The CAS number of 14-Hydroxyclarithromycin is 110671-78-8.
What is the molecular formula of 14-Hydroxyclarithromycin?
The molecular formula of 14-Hydroxyclarithromycin is C38H69NO14.
What is the molecular weight of 14-Hydroxyclarithromycin?
The molecular weight of 14-Hydroxyclarithromycin is 763.4718 g/mol.
Where can I buy 14-Hydroxyclarithromycin?
You can request a quote for 14-Hydroxyclarithromycin directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 14-Hydroxyclarithromycin?
Yes, CoreyChem provides custom synthesis services for 14-Hydroxyclarithromycin and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.