Methyl Salicylate
TL;DR: Methyl Salicylate (CAS 119-36-8) is a chemical compound with molecular formula C8H8O3 and molecular weight 152.04735 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
methyl 2-hydroxybenzoate
Also Known As: methyl salicylate, Methyl 2-hydroxybenzoate, Wintergreen oil, Gaultheria oil, Analgit
Application Areas
Top 5 of 22 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C8H8O3 |
| Molecular Weight | 152.04735 g/mol |
| XLogP | 2.3 |
| Topological Polar Surface Area (TPSA) | 46.5 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 2 |
| Exact Mass | 152.04735 Da |
| Heavy Atoms | 11 |
| Complexity | 144.0 |
| Purity | ≥98% |
| Melting Point | 16.5 °F (NTP, 1992) |
| Boiling Point | 432 °F at 760 mmHg (NTP, 1992) |
| Density | 1.174 (USCG, 1999) - Denser than water; will sink |
| Flash Point | 205 °F (NTP, 1992) |
| Vapor Pressure | 0.0975 mmHg at 68 °F ; 1 mmHg at 129 °F (NTP, 1992) |
| Refractive Index | INDEX OF REFRACTION: 1.5369 AT 20 °C/D; MAX ABSORPTION: 306 NM (LOG E= 3.64); SADTLER REFERENCE NUMBER: 2238 (IR, PRISM); MAX ABSORPTION (ALC): 238 NM (LOG E= 3.97) |
| Solubility | less than 1 mg/mL at 66 °F (NTP, 1992) |
| SMILES | COC(=O)C1=CC=CC=C1O |
| InChIKey | OSWPMRLSEDHDFF-UHFFFAOYSA-N |
Product Description
Applications: Methyl Salicylate is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Product profile: commercial lots are supplied at ≥98%. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
A pharmaceutical intermediate supplied by CoreyChem, Methyl Salicylate (CAS 119-36-8) has the molecular formula C8H8O3 and a molecular weight of 152.05 g/mol. Reported properties include a density of 1.174 (USCG, 1999) - Denser than water; will sink g/cm³, a solubility: less than 1 mg/mL at 66 °F (NTP, 1992). Synonyms include methyl salicylate and Methyl 2-hydroxybenzoate.
Custom synthesis (mg to ton scale), HPLC/NMR/MS analytical support, and complete COA/MSDS documentation are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Safety Information
H302, H317, H318, H361d, H412
Chemical Property Profile of Methyl Salicylate
Property Insights of Methyl Salicylate
The XLogP value of 2.3 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Methyl Salicylate. With a topological polar surface area (TPSA) of 46.5 Ų, Methyl Salicylate exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Methyl Salicylate has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Methyl Salicylate?
The CAS number of Methyl Salicylate is 119-36-8.
What is the molecular formula of Methyl Salicylate?
The molecular formula of Methyl Salicylate is C8H8O3.
What is the molecular weight of Methyl Salicylate?
The molecular weight of Methyl Salicylate is 152.04735 g/mol.
What are the applications of Methyl Salicylate?
Methyl Salicylate is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Product profile: commercial lots are supplied at ≥98%....
Where can I buy Methyl Salicylate?
You can request a quote for Methyl Salicylate directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Methyl Salicylate?
Yes, CoreyChem provides custom synthesis services for Methyl Salicylate and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.