10-chloro-(20RS)-camptothecin
TL;DR: 10-chloro-(20RS)-camptothecin (CAS 119529-48-5) is a chemical compound with molecular formula C20H15ClN2O4 and molecular weight 382.07202 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
7-chloro-19-ethyl-19-hydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2(11),3,5,7,9,15(20)-heptaene-14,18-dione
Also Known As: 10-chloro-(20RS)-camptothecin, 10-Chloro-20(RS)-Camptothecin, 10-Chloro-20-(RS)-Camptothecin, 1H-Pyrano(3',4':6,7)indolizino(1,2-b)quinoline-3,14(4H,12H)-dione, 9-chloro-4-ethyl-4-hydroxy-, 1H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione,9-chloro-4-ethyl-4-hydroxy-
Application Areas
Top 5 of 1 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C20H15ClN2O4 |
| Molecular Weight | 382.07202 g/mol |
| XLogP | 1.6 |
| Topological Polar Surface Area (TPSA) | 79.7 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 1 |
| Exact Mass | 382.07202 Da |
| Heavy Atoms | 27 |
| Complexity | 778.0 |
| SMILES | CCC1(C2=C(COC1=O)C(=O)N3CC4=C(C3=C2)N=C5C=CC(=CC5=C4)Cl)O |
| InChIKey | MXIBGRFZFZXAKG-UHFFFAOYSA-N |
Chemical Property Profile of 10-chloro-(20RS)-camptothecin
Property Insights of 10-chloro-(20RS)-camptothecin
The XLogP value of 1.6 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 10-chloro-(20RS)-camptothecin. The TPSA of 79.7 Ų falls within the moderate polarity range, balancing permeability and solubility for 10-chloro-(20RS)-camptothecin. Following Lipinski's Rule of Five, 10-chloro-(20RS)-camptothecin has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of 10-chloro-(20RS)-camptothecin?
The CAS number of 10-chloro-(20RS)-camptothecin is 119529-48-5.
What is the molecular formula of 10-chloro-(20RS)-camptothecin?
The molecular formula of 10-chloro-(20RS)-camptothecin is C20H15ClN2O4.
What is the molecular weight of 10-chloro-(20RS)-camptothecin?
The molecular weight of 10-chloro-(20RS)-camptothecin is 382.07202 g/mol.
Where can I buy 10-chloro-(20RS)-camptothecin?
You can request a quote for 10-chloro-(20RS)-camptothecin directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 10-chloro-(20RS)-camptothecin?
Yes, CoreyChem provides custom synthesis services for 10-chloro-(20RS)-camptothecin and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.