TL;DR: N-(((9H-Fluoren-9-yl)methoxy)carbonyl)leucine (CAS 126727-03-5) is a chemical compound with molecular formula C21H23NO4 and molecular weight 353.16272 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
2-(9H-fluoren-9-ylmethoxycarbonylamino)-4-methylpentanoic acid
Also Known As: Fmoc-L-leucine, Fmoc-D-leucine, Fmoc-DL-leucine, Fmoc-Leu-OH, Fmoc-D-Leu-OH
Top 5 of 5 IPC patent classification(s) from the SureChEMBL global patent database.
| Molecular Formula | C21H23NO4 |
| Molecular Weight | 353.16272 g/mol |
| XLogP | 4.4 |
| Topological Polar Surface Area (TPSA) | 75.6 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 7 |
| Exact Mass | 353.16272 Da |
| Heavy Atoms | 26 |
| Complexity | 484.0 |
| SMILES | CC(C)CC(C(=O)O)NC(=O)OCC1C2=CC=CC=C2C3=CC=CC=C13 |
| InChIKey | CBPJQFCAFFNICX-UHFFFAOYSA-N |
The XLogP value of 4.4 indicates that N-(((9H-Fluoren-9-yl)methoxy)carbonyl)leucine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 75.6 Ų falls within the moderate polarity range, balancing permeability and solubility for N-(((9H-Fluoren-9-yl)methoxy)carbonyl)leucine. Following Lipinski's Rule of Five, N-(((9H-Fluoren-9-yl)methoxy)carbonyl)leucine has 2 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
The CAS number of N-(((9H-Fluoren-9-yl)methoxy)carbonyl)leucine is 126727-03-5.
The molecular formula of N-(((9H-Fluoren-9-yl)methoxy)carbonyl)leucine is C21H23NO4.
The molecular weight of N-(((9H-Fluoren-9-yl)methoxy)carbonyl)leucine is 353.16272 g/mol.
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