N-(((9H-Fluoren-9-yl)methoxy)carbonyl)leucine
TL;DR: N-(((9H-Fluoren-9-yl)methoxy)carbonyl)leucine (CAS 126727-03-5) is a chemical compound with molecular formula C21H23NO4 and molecular weight 353.16272 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
2-(9H-fluoren-9-ylmethoxycarbonylamino)-4-methylpentanoic acid
Also Known As: Fmoc-L-leucine, Fmoc-D-leucine, Fmoc-DL-leucine, Fmoc-Leu-OH, Fmoc-D-Leu-OH
Application Areas
Top 5 of 5 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C21H23NO4 |
| Molecular Weight | 353.16272 g/mol |
| XLogP | 4.4 |
| Topological Polar Surface Area (TPSA) | 75.6 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 7 |
| Exact Mass | 353.16272 Da |
| Heavy Atoms | 26 |
| Complexity | 484.0 |
| SMILES | CC(C)CC(C(=O)O)NC(=O)OCC1C2=CC=CC=C2C3=CC=CC=C13 |
| InChIKey | CBPJQFCAFFNICX-UHFFFAOYSA-N |
Product Description
Applications: N-(((9H-Fluoren-9-yl)methoxy)carbonyl)leucine is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
N-(((9H-Fluoren-9-yl)methoxy)carbonyl)leucine is a pharmaceutical intermediate identified by CAS number 126727-03-5 and the molecular formula C21H23NO4 and a molecular weight of 353.16 g/mol. Synonyms include Fmoc-L-leucine and Fmoc-D-leucine.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of N-(((9H-Fluoren-9-yl)methoxy)carbonyl)leucine
Property Insights of N-(((9H-Fluoren-9-yl)methoxy)carbonyl)leucine
The XLogP value of 4.4 indicates that N-(((9H-Fluoren-9-yl)methoxy)carbonyl)leucine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 75.6 Ų falls within the moderate polarity range, balancing permeability and solubility for N-(((9H-Fluoren-9-yl)methoxy)carbonyl)leucine. Following Lipinski's Rule of Five, N-(((9H-Fluoren-9-yl)methoxy)carbonyl)leucine has 2 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of N-(((9H-Fluoren-9-yl)methoxy)carbonyl)leucine?
The CAS number of N-(((9H-Fluoren-9-yl)methoxy)carbonyl)leucine is 126727-03-5.
What is the molecular formula of N-(((9H-Fluoren-9-yl)methoxy)carbonyl)leucine?
The molecular formula of N-(((9H-Fluoren-9-yl)methoxy)carbonyl)leucine is C21H23NO4.
What is the molecular weight of N-(((9H-Fluoren-9-yl)methoxy)carbonyl)leucine?
The molecular weight of N-(((9H-Fluoren-9-yl)methoxy)carbonyl)leucine is 353.16272 g/mol.
What are the applications of N-(((9H-Fluoren-9-yl)methoxy)carbonyl)leucine?
N-(((9H-Fluoren-9-yl)methoxy)carbonyl)leucine is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as...
Where can I buy N-(((9H-Fluoren-9-yl)methoxy)carbonyl)leucine?
You can request a quote for N-(((9H-Fluoren-9-yl)methoxy)carbonyl)leucine directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for N-(((9H-Fluoren-9-yl)methoxy)carbonyl)leucine?
Yes, CoreyChem provides custom synthesis services for N-(((9H-Fluoren-9-yl)methoxy)carbonyl)leucine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.