Hydroxyurea
TL;DR: Hydroxyurea (CAS 127-07-1) is a chemical compound with molecular formula CH4N2O2 and molecular weight 76.027275 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
hydroxyurea
Also Known As: hydroxyurea, Hydroxycarbamide, Hydrea, N-Hydroxyurea, Oxyurea
Application Areas
Top 5 of 20 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | CH4N2O2 |
| Molecular Weight | 76.027275 g/mol |
| XLogP | -1.8 |
| Topological Polar Surface Area (TPSA) | 75.4 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 0 |
| Exact Mass | 76.027275 Da |
| Heavy Atoms | 5 |
| Complexity | 42.0 |
| Melting Point | 291 to 295 °F (decomposes) (NTP, 1992) |
| Boiling Point | Decomposes (NTP, 1992) |
| Solubility | greater than or equal to 100 mg/mL at 70 °F (NTP, 1992) |
| SMILES | C(=O)(N)NO |
| InChIKey | VSNHCAURESNICA-UHFFFAOYSA-N |
Product Description
Applications: Hydroxyurea is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
Hydroxyurea is a pharmaceutical intermediate identified by CAS number 127-07-1 and the molecular formula CH4N2O2 and a molecular weight of 76.03 g/mol. Physically, the compound has a solubility: greater than or equal to 100 mg/mL at 70 °F (NTP, 1992). Synonyms include hydroxyurea and Hydroxycarbamide.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Hydroxyurea
Property Insights of Hydroxyurea
The XLogP value of -1.8 indicates that Hydroxyurea is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 75.4 Ų falls within the moderate polarity range, balancing permeability and solubility for Hydroxyurea. Following Lipinski's Rule of Five, Hydroxyurea has 3 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Hydroxyurea?
The CAS number of Hydroxyurea is 127-07-1.
What is the molecular formula of Hydroxyurea?
The molecular formula of Hydroxyurea is CH4N2O2.
What is the molecular weight of Hydroxyurea?
The molecular weight of Hydroxyurea is 76.027275 g/mol.
What are the applications of Hydroxyurea?
Hydroxyurea is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and...
Where can I buy Hydroxyurea?
You can request a quote for Hydroxyurea directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Hydroxyurea?
Yes, CoreyChem provides custom synthesis services for Hydroxyurea and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.