Clioquinol
TL;DR: Clioquinol (CAS 130-26-7) is a chemical compound with molecular formula C9H5ClINO and molecular weight 304.91043 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
5-chloro-7-iodoquinolin-8-ol
Also Known As: clioquinol, 5-Chloro-7-iodoquinolin-8-ol, Iodochlorhydroxyquin, Chinoform, Chloroiodoquin
Application Areas
Top 5 of 18 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C9H5ClINO |
| Molecular Weight | 304.91043 g/mol |
| XLogP | 3.5 |
| Topological Polar Surface Area (TPSA) | 33.1 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 0 |
| Exact Mass | 304.91043 Da |
| Heavy Atoms | 13 |
| Complexity | 192.0 |
| Melting Point | 352 to 354 °F (NTP, 1992) |
| Solubility | less than 1 mg/mL at 68 °F (NTP, 1992) |
| SMILES | C1=CC2=C(C(=C(C=C2Cl)I)O)N=C1 |
| InChIKey | QCDFBFJGMNKBDO-UHFFFAOYSA-N |
Product Description
Applications: Clioquinol is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies Clioquinol (CAS 130-26-7) with custom synthesis available from milligram to multi-kilogram scale, supported by COA, MSDS, and HPLC/NMR/MS documentation.
Clioquinol (CAS 130-26-7) is a pharmaceutical intermediate with the molecular formula C9H5ClINO and a molecular weight of 304.91 g/mol. Key physical properties include a solubility: less than 1 mg/mL at 68 °F (NTP, 1992). It is also known as clioquinol and 5-Chloro-7-iodoquinolin-8-ol.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Clioquinol
Property Insights of Clioquinol
The XLogP value of 3.5 indicates that Clioquinol is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 33.1 Ų, Clioquinol exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Clioquinol has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Clioquinol?
The CAS number of Clioquinol is 130-26-7.
What is the molecular formula of Clioquinol?
The molecular formula of Clioquinol is C9H5ClINO.
What is the molecular weight of Clioquinol?
The molecular weight of Clioquinol is 304.91043 g/mol.
What are the applications of Clioquinol?
Clioquinol is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies Clioquinol (CAS 130-26-7) with custom...
Where can I buy Clioquinol?
You can request a quote for Clioquinol directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Clioquinol?
Yes, CoreyChem provides custom synthesis services for Clioquinol and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.