AM251
TL;DR: AM251 (CAS 183232-66-8) is a chemical compound with molecular formula C22H21Cl2IN4O and molecular weight 554.01373 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
nchembio.86-comp7
1-(2,4-dichlorophenyl)-5-(4-iodophenyl)-4-methyl-N-piperidin-1-ylpyrazole-3-carboxamide
Also Known As: AM251, AM 251, (S)-6-Hydroxy Nicotine, nchembio.86-comp7, AM 251 (pharmaceutical)
Application Areas
Top 5 of 4 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C22H21Cl2IN4O |
| Molecular Weight | 554.01373 g/mol |
| XLogP | 6.5 |
| Topological Polar Surface Area (TPSA) | 50.2 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 4 |
| Exact Mass | 554.01373 Da |
| Heavy Atoms | 30 |
| Complexity | 585.0 |
| SMILES | CC1=C(N(N=C1C(=O)NN2CCCCC2)C3=C(C=C(C=C3)Cl)Cl)C4=CC=C(C=C4)I |
| InChIKey | BUZAJRPLUGXRAB-UHFFFAOYSA-N |
Product Description
Applications: AM251 is used in pharmaceutical synthesis routes and API production, as well as analytical chemistry as a reagent, standard, or reference material. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
A pharmaceutical intermediate supplied by CoreyChem, AM251 (CAS 183232-66-8) has the molecular formula C22H21Cl2IN4O and a molecular weight of 554.01 g/mol. Synonyms include AM251 and AM-251.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of AM251
Property Insights of AM251
The XLogP value of 6.5 indicates that AM251 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 50.2 Ų, AM251 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, AM251 has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
What is the CAS number of AM251?
The CAS number of AM251 is 183232-66-8.
What is the molecular formula of AM251?
The molecular formula of AM251 is C22H21Cl2IN4O.
What is the molecular weight of AM251?
The molecular weight of AM251 is 554.01373 g/mol.
What are the applications of AM251?
AM251 is used in pharmaceutical synthesis routes and API production, as well as analytical chemistry as a reagent, standard, or reference material. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project...
Where can I buy AM251?
You can request a quote for AM251 directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for AM251?
Yes, CoreyChem provides custom synthesis services for AM251 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.