2-Naphthol
TL;DR: 2-Naphthol (CAS 135-19-3) is a chemical compound with molecular formula C10H8O and molecular weight 144.05751 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
naphthalen-2-ol
Also Known As: 2-NAPHTHOL, naphthalen-2-ol, 2-Naphthalenol, beta-naphthol, Betanaphthol
Application Areas
Top 5 of 22 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C10H8O |
| Molecular Weight | 144.05751 g/mol |
| XLogP | 2.7 |
| Topological Polar Surface Area (TPSA) | 20.2 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 1 |
| Rotatable Bonds | 0 |
| Exact Mass | 144.05751 Da |
| Heavy Atoms | 11 |
| Complexity | 133.0 |
| Melting Point | 121.6 °C |
| Boiling Point | 285 °C |
| Density | 1.28 g/cu cm at 20 °C |
| Flash Point | 152.7 °C |
| Vapor Pressure | VP: 9.9 mm Hg at 144 °C |
| Solubility | In water, 7.55X10+2 mg/L at 25 °C |
| SMILES | C1=CC=C2C=C(C=CC2=C1)O |
| InChIKey | JWAZRIHNYRIHIV-UHFFFAOYSA-N |
Product Description
Applications: 2-Naphthol is used in heterocycle construction in medicinal chemistry and agrochemical discovery, as well as pharmaceutical synthesis routes and API production. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies 2-Naphthol (CAS 135-19-3) with custom synthesis available from milligram to multi-kilogram scale, supported by COA, MSDS, and HPLC/NMR/MS documentation.
2-Naphthol is a heterocyclic building block identified by CAS number 135-19-3 and the molecular formula C10H8O and a molecular weight of 144.06 g/mol. Physically, the compound has a density of 1.28 g/cu cm at 20 °C g/cm³, a solubility: In water, 7.55X10+2 mg/L at 25 °C. It is also known as 2-NAPHTHOL and naphthalen-2-ol.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of 2-Naphthol
Property Insights of 2-Naphthol
The XLogP value of 2.7 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 2-Naphthol. With a topological polar surface area (TPSA) of 20.2 Ų, 2-Naphthol exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 2-Naphthol has 1 hydrogen bond donor(s) and 1 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of 2-Naphthol?
The CAS number of 2-Naphthol is 135-19-3.
What is the molecular formula of 2-Naphthol?
The molecular formula of 2-Naphthol is C10H8O.
What is the molecular weight of 2-Naphthol?
The molecular weight of 2-Naphthol is 144.05751 g/mol.
What are the applications of 2-Naphthol?
2-Naphthol is used in heterocycle construction in medicinal chemistry and agrochemical discovery, as well as pharmaceutical synthesis routes and API production. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies 2-Naphthol (CAS 135-19-3) with custom...
Where can I buy 2-Naphthol?
You can request a quote for 2-Naphthol directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 2-Naphthol?
Yes, CoreyChem provides custom synthesis services for 2-Naphthol and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.