NIP 121
TL;DR: NIP 121 (CAS 135244-62-1) is a chemical compound with molecular formula C16H19N3O4 and molecular weight 317.13754 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
1-[(7R,8S)-7-hydroxy-6,6-dimethyl-7,8-dihydropyrano[2,3-f][2,1,3]benzoxadiazol-8-yl]piperidin-2-one
Also Known As: NIP 121, NIP 1, 2-Piperidinone, 1-(7,8-dihydro-7-hydroxy-6,6-dimethyl-6H-pyrano(2,3-f)-2,1,3-benzoxadiazol-8-yl)-, trans-(+)-, 7,8-Dihydro-6,6-dimethyl-7-hydroxy-8-(2-oxo-piperidin-1-yl)-6H-pyrano(2,3)benz-2,1,3-oxadiazole, 1-[(7R,8S)-7-hydroxy-6,6-dimethyl-7,8-dihydropyrano[2,3-f][2,1,3]benzoxadiazol-8-yl]piperidin-2-one
Application Areas
Top 5 of 1 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C16H19N3O4 |
| Molecular Weight | 317.13754 g/mol |
| XLogP | 0.7 |
| Topological Polar Surface Area (TPSA) | 88.7 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 1 |
| Exact Mass | 317.13754 Da |
| Heavy Atoms | 23 |
| Complexity | 486.0 |
| SMILES | CC1([C@@H]([C@H](C2=CC3=NON=C3C=C2O1)N4CCCCC4=O)O)C |
| InChIKey | KMXPHBJUGYLXDM-LSDHHAIUSA-N |
Chemical Property Profile of NIP 121
Property Insights of NIP 121
The XLogP value of 0.7 suggests moderate lipophilicity, balancing water solubility and membrane permeability for NIP 121. The TPSA of 88.7 Ų falls within the moderate polarity range, balancing permeability and solubility for NIP 121. Following Lipinski's Rule of Five, NIP 121 has 1 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of NIP 121?
The CAS number of NIP 121 is 135244-62-1.
What is the molecular formula of NIP 121?
The molecular formula of NIP 121 is C16H19N3O4.
What is the molecular weight of NIP 121?
The molecular weight of NIP 121 is 317.13754 g/mol.
Where can I buy NIP 121?
You can request a quote for NIP 121 directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for NIP 121?
Yes, CoreyChem provides custom synthesis services for NIP 121 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.