Nefopam
TL;DR: Nefopam (CAS 13669-70-0) is a chemical compound with molecular formula C17H19NO and molecular weight 253.14667 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
5-methyl-1-phenyl-1,3,4,6-tetrahydro-2,5-benzoxazocine
Also Known As: nefopam, Fenazoxine, Nefopamum, Sinalgico, Acupan
Application Areas
Top 5 of 12 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C17H19NO |
| Molecular Weight | 253.14667 g/mol |
| XLogP | 2.9 |
| Topological Polar Surface Area (TPSA) | 12.5 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 1 |
| Exact Mass | 253.14667 Da |
| Heavy Atoms | 19 |
| Complexity | 274.0 |
| SMILES | CN1CCOC(C2=CC=CC=C2C1)C3=CC=CC=C3 |
| InChIKey | RGPDEAGGEXEMMM-UHFFFAOYSA-N |
Product Description
Applications: Nefopam is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
Nefopam is a pharmaceutical intermediate identified by CAS number 13669-70-0 and the molecular formula C17H19NO and a molecular weight of 253.15 g/mol. Synonyms include nefopam and Fenazoxine.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Nefopam
Property Insights of Nefopam
The XLogP value of 2.9 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Nefopam. With a topological polar surface area (TPSA) of 12.5 Ų, Nefopam exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Nefopam has 0 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Nefopam?
The CAS number of Nefopam is 13669-70-0.
What is the molecular formula of Nefopam?
The molecular formula of Nefopam is C17H19NO.
What is the molecular weight of Nefopam?
The molecular weight of Nefopam is 253.14667 g/mol.
What are the applications of Nefopam?
Nefopam is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis...
Where can I buy Nefopam?
You can request a quote for Nefopam directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Nefopam?
Yes, CoreyChem provides custom synthesis services for Nefopam and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.