buprenorphine
TL;DR: buprenorphine (CAS 136781-89-0) is a chemical compound with molecular formula C29H41NO4 and molecular weight 467.30356 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
5-(cyclopropylmethyl)-16-(2-hydroxy-3,3-dimethylbutan-2-yl)-15-methoxy-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-trien-11-ol
Also Known As: buprenorphine, Temgesic, DEA No. 9064, RX 6029M, Buprenorphine-d4 (cyclopropyl-2,2,3,3-d4) hydrochloride
Technical Specifications
| Molecular Formula | C29H41NO4 |
| Molecular Weight | 467.30356 g/mol |
| XLogP | 5.0 |
| Topological Polar Surface Area (TPSA) | 62.2 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 5 |
| Exact Mass | 467.30356 Da |
| Heavy Atoms | 34 |
| Complexity | 869.0 |
| SMILES | CC(C)(C)C(C)(C1CC23CCC1(C4C25CCN(C3CC6=C5C(=C(C=C6)O)O4)CC7CC7)OC)O |
| InChIKey | RMRJXGBAOAMLHD-UHFFFAOYSA-N |
Chemical Property Profile of buprenorphine
Property Insights of buprenorphine
The XLogP value of 5.0 indicates that buprenorphine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 62.2 Ų falls within the moderate polarity range, balancing permeability and solubility for buprenorphine. Following Lipinski's Rule of Five, buprenorphine has 2 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of buprenorphine?
The CAS number of buprenorphine is 136781-89-0.
What is the molecular formula of buprenorphine?
The molecular formula of buprenorphine is C29H41NO4.
What is the molecular weight of buprenorphine?
The molecular weight of buprenorphine is 467.30356 g/mol.
Where can I buy buprenorphine?
You can request a quote for buprenorphine directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for buprenorphine?
Yes, CoreyChem provides custom synthesis services for buprenorphine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.