Enflurane
TL;DR: Enflurane (CAS 13838-16-9) is a chemical compound with molecular formula C3H2ClF5O and molecular weight 183.97144 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
2-chloro-1-(difluoromethoxy)-1,1,2-trifluoroethane
Also Known As: enflurane, Methylflurether, Ethrane, Efrane, Alyrane
Application Areas
Top 5 of 13 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C3H2ClF5O |
| Molecular Weight | 183.97144 g/mol |
| XLogP | 2.1 |
| Topological Polar Surface Area (TPSA) | 9.2 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 3 |
| Exact Mass | 183.97144 Da |
| Heavy Atoms | 10 |
| Complexity | 107.0 |
| Melting Point | 48.5 |
| Boiling Point | 134 °F at 760 mmHg (NIOSH, 2024) |
| Density | 1.52 at 77 °F (NIOSH, 2024) - Denser than water; will sink |
| Vapor Pressure | 175 mmHg (NIOSH, 2024) |
| Solubility | Low (NIOSH, 2024) |
| SMILES | C(C(OC(F)F)(F)F)(F)Cl |
| InChIKey | JPGQOUSTVILISH-UHFFFAOYSA-N |
Product Description
Applications: Enflurane is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
Enflurane is a pharmaceutical intermediate identified by CAS number 13838-16-9 and the molecular formula C3H2ClF5O and a molecular weight of 183.97 g/mol. Physically, the compound has a density of 1.52 at 77 °F (NIOSH, 2024) - Denser than water; will sink g/cm³, a solubility: Low (NIOSH, 2024). Synonyms include enflurane and Methylflurether.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Enflurane
Property Insights of Enflurane
The XLogP value of 2.1 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Enflurane. With a topological polar surface area (TPSA) of 9.2 Ų, Enflurane exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Enflurane has 0 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Enflurane?
The CAS number of Enflurane is 13838-16-9.
What is the molecular formula of Enflurane?
The molecular formula of Enflurane is C3H2ClF5O.
What is the molecular weight of Enflurane?
The molecular weight of Enflurane is 183.97144 g/mol.
What are the applications of Enflurane?
Enflurane is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and...
Where can I buy Enflurane?
You can request a quote for Enflurane directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Enflurane?
Yes, CoreyChem provides custom synthesis services for Enflurane and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.