Clobetasonebutyrate
TL;DR: Clobetasonebutyrate (CAS 25122-57-0) is a chemical compound with molecular formula C26H32ClFO5 and molecular weight 478.19223 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
[17-(2-chloroacetyl)-9-fluoro-10,13,16-trimethyl-3,11-dioxo-7,8,12,14,15,16-hexahydro-6H-cyclopenta[a]phenanthren-17-yl] butanoate
Also Known As: Clobetasonebutyrate, clobetasone butyrate, 16?-Methyl clobetasone butyrate, [17-(2-chloroacetyl)-9-fluoro-10,13,16-trimethyl-3,11-dioxo-7,8,12,14,15,16-hexahydro-6H-cyclopenta[a]phenanthren-17-yl] butanoate, 14-(2-chloroacetyl)-1-fluoro-2,13,15-trimethyl-5,17-dioxotetracyclo[8.7.0.0<2, 7>.0<11,15>]heptadeca-3,6-dien-14-yl butanoate
Application Areas
Top 5 of 1 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C26H32ClFO5 |
| Molecular Weight | 478.19223 g/mol |
| XLogP | 3.8 |
| Topological Polar Surface Area (TPSA) | 77.5 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 6 |
| Exact Mass | 478.19223 Da |
| Heavy Atoms | 33 |
| Complexity | 987.0 |
| SMILES | CCCC(=O)OC1(C(CC2C1(CC(=O)C3(C2CCC4=CC(=O)C=CC43C)F)C)C)C(=O)CCl |
| InChIKey | FBRAWBYQGRLCEK-UHFFFAOYSA-N |
Chemical Property Profile of Clobetasonebutyrate
Property Insights of Clobetasonebutyrate
The XLogP value of 3.8 indicates that Clobetasonebutyrate is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 77.5 Ų falls within the moderate polarity range, balancing permeability and solubility for Clobetasonebutyrate. Following Lipinski's Rule of Five, Clobetasonebutyrate has 0 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Clobetasonebutyrate?
The CAS number of Clobetasonebutyrate is 25122-57-0.
What is the molecular formula of Clobetasonebutyrate?
The molecular formula of Clobetasonebutyrate is C26H32ClFO5.
What is the molecular weight of Clobetasonebutyrate?
The molecular weight of Clobetasonebutyrate is 478.19223 g/mol.
Where can I buy Clobetasonebutyrate?
You can request a quote for Clobetasonebutyrate directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Clobetasonebutyrate?
Yes, CoreyChem provides custom synthesis services for Clobetasonebutyrate and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.