4,4-Difluoropyrrolidine-2-carboxylic acid
TL;DR: 4,4-Difluoropyrrolidine-2-carboxylic acid (CAS 1401332-74-8) is a chemical compound with molecular formula C5H7F2NO2 and molecular weight 151.04448 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
4,4-difluoropyrrolidine-2-carboxylic acid
Also Known As: 4,4-difluoropyrrolidine-2-carboxylic acid, 4,4-Difluoroproline, 4,4-Difluoro-L-proline, (S)-4,4-Difluoropyrrolidine-2-carboxylic acid, 4,4-difluoropyrrolidine-2-carboxylicacid
Technical Specifications
| Molecular Formula | C5H7F2NO2 |
| Molecular Weight | 151.04448 g/mol |
| XLogP | -2.1 |
| Topological Polar Surface Area (TPSA) | 49.3 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 1 |
| Exact Mass | 151.04448 Da |
| Heavy Atoms | 10 |
| Complexity | 160.0 |
| SMILES | C1C(NCC1(F)F)C(=O)O |
| InChIKey | ZPBIYZHGBPBZCK-UHFFFAOYSA-N |
Chemical Property Profile of 4,4-Difluoropyrrolidine-2-carboxylic acid
Property Insights of 4,4-Difluoropyrrolidine-2-carboxylic acid
The XLogP value of -2.1 indicates that 4,4-Difluoropyrrolidine-2-carboxylic acid is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. With a topological polar surface area (TPSA) of 49.3 Ų, 4,4-Difluoropyrrolidine-2-carboxylic acid exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 4,4-Difluoropyrrolidine-2-carboxylic acid has 2 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of 4,4-Difluoropyrrolidine-2-carboxylic acid?
The CAS number of 4,4-Difluoropyrrolidine-2-carboxylic acid is 1401332-74-8.
What is the molecular formula of 4,4-Difluoropyrrolidine-2-carboxylic acid?
The molecular formula of 4,4-Difluoropyrrolidine-2-carboxylic acid is C5H7F2NO2.
What is the molecular weight of 4,4-Difluoropyrrolidine-2-carboxylic acid?
The molecular weight of 4,4-Difluoropyrrolidine-2-carboxylic acid is 151.04448 g/mol.
Where can I buy 4,4-Difluoropyrrolidine-2-carboxylic acid?
You can request a quote for 4,4-Difluoropyrrolidine-2-carboxylic acid directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 4,4-Difluoropyrrolidine-2-carboxylic acid?
Yes, CoreyChem provides custom synthesis services for 4,4-Difluoropyrrolidine-2-carboxylic acid and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.