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Gentamicin structure
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Gentamicin

TL;DR: Gentamicin (CAS 1403-66-3) is a chemical compound with molecular formula C21H43N5O7 and molecular weight 477.31625 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.

2-[4,6-diamino-3-[3-amino-6-[1-(methylamino)ethyl]oxan-2-yl]oxy-2-hydroxycyclohexyl]oxy-5-methyl-4-(methylamino)oxane-3,5-diol

Also Known As: gentamicin, Gentacycol, Garamycin, Uromycine, Gentamycinum

CAS Number
1403-66-3
Molecular Formula
C21H43N5O7
Molecular Weight
477.31625 g/mol
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Application Areas

Top 5 of 5 IPC patent classification(s) from the SureChEMBL global patent database.

Analytical Reagents (1 patents) Biotechnology (7 patents) Heterocyclic Building Blocks (3 patents) Peptides & Amino Acids (30 patents) Pharmaceutical Intermediates (60 patents)

Technical Specifications

Molecular FormulaC21H43N5O7
Molecular Weight477.31625 g/mol
XLogP-4.1
Topological Polar Surface Area (TPSA)200.0 Ų
Hydrogen Bond Donors8
Hydrogen Bond Acceptors12
Rotatable Bonds7
Exact Mass477.31625 Da
Heavy Atoms33
Complexity636.0
Melting Point105
SolubilityFreely soluble in water
SMILESCC(C1CCC(C(O1)OC2C(CC(C(C2O)OC3C(C(C(CO3)(C)O)NC)O)N)N)N)NC
InChIKeyCEAZRRDELHUEMR-UHFFFAOYSA-N

Product Description

Applications: Gentamicin is used in pharmaceutical synthesis routes and API production, as well as peptide synthesis and amino acid derivative chemistry. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies Gentamicin (CAS 1403-66-3) with custom synthesis available from milligram to multi-kilogram scale, supported by COA, MSDS, and HPLC/NMR/MS documentation.

A pharmaceutical intermediate supplied by CoreyChem, Gentamicin (CAS 1403-66-3) has the molecular formula C21H43N5O7 and a molecular weight of 477.32 g/mol. Reported properties include a solubility: Freely soluble in water. It is also known as gentamicin and Gentacycol.

Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.

Chemical Property Profile of Gentamicin

XLogP
-4.1
TPSA (Topological Polar Surface Area)
200.0
Hydrogen Bond Donors
8
Hydrogen Bond Acceptors
12
Rotatable Bonds
7
Heavy Atoms
33
Complexity
636.0
Exact Mass
477.31625
Monoisotopic Mass
477.31625
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Gentamicin

The XLogP value of -4.1 indicates that Gentamicin is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 200.0 Ų indicates high polarity, suggesting Gentamicin may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Gentamicin has 8 hydrogen bond donor(s) and 12 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the CAS number of Gentamicin?

The CAS number of Gentamicin is 1403-66-3.

What is the molecular formula of Gentamicin?

The molecular formula of Gentamicin is C21H43N5O7.

What is the molecular weight of Gentamicin?

The molecular weight of Gentamicin is 477.31625 g/mol.

What are the applications of Gentamicin?

Gentamicin is used in pharmaceutical synthesis routes and API production, as well as peptide synthesis and amino acid derivative chemistry. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies Gentamicin (CAS 1403-66-3) with custom synthesis available from...

Where can I buy Gentamicin?

You can request a quote for Gentamicin directly from CoreyChem. Contact us or email [email protected] for pricing and availability.

Does CoreyChem offer custom synthesis for Gentamicin?

Yes, CoreyChem provides custom synthesis services for Gentamicin and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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