Malonic Acid
TL;DR: Malonic Acid (CAS 141-82-2) is a chemical compound with molecular formula C3H4O4 and molecular weight 104.010956 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
propanedioic acid
Also Known As: malonic acid, propanedioic acid, Dicarboxymethane, malonate, Carboxyacetic acid
Application Areas
Top 5 of 22 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C3H4O4 |
| Molecular Weight | 104.010956 g/mol |
| XLogP | -0.8 |
| Topological Polar Surface Area (TPSA) | 74.6 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 2 |
| Exact Mass | 104.010956 Da |
| Heavy Atoms | 7 |
| Complexity | 83.0 |
| Melting Point | 276.1 °F (NTP, 1992) |
| Boiling Point | 284 °F at 760 mmHg (decomposes) (NTP, 1992) |
| Density | 1.63 (NTP, 1992) - Denser than water; will sink |
| Vapor Pressure | 0.0015 [mmHg] |
| Solubility | greater than or equal to 100 mg/mL at 72 °F (NTP, 1992) |
| SMILES | C(C(=O)O)C(=O)O |
| InChIKey | OFOBLEOULBTSOW-UHFFFAOYSA-N |
Product Description
Applications: Malonic Acid is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
Malonic Acid (CAS 141-82-2) is a pharmaceutical intermediate with the molecular formula C3H4O4 and a molecular weight of 104.01 g/mol. Key physical properties include a density of 1.63 (NTP, 1992) - Denser than water; will sink g/cm³, a solubility: greater than or equal to 100 mg/mL at 72 °F (NTP, 1992). Synonyms include malonic acid and propanedioic acid.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Malonic Acid
Property Insights of Malonic Acid
The XLogP value of -0.8 indicates that Malonic Acid is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 74.6 Ų falls within the moderate polarity range, balancing permeability and solubility for Malonic Acid. Following Lipinski's Rule of Five, Malonic Acid has 2 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Malonic Acid?
The CAS number of Malonic Acid is 141-82-2.
What is the molecular formula of Malonic Acid?
The molecular formula of Malonic Acid is C3H4O4.
What is the molecular weight of Malonic Acid?
The molecular weight of Malonic Acid is 104.010956 g/mol.
What are the applications of Malonic Acid?
Malonic Acid is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and...
Where can I buy Malonic Acid?
You can request a quote for Malonic Acid directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Malonic Acid?
Yes, CoreyChem provides custom synthesis services for Malonic Acid and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.