Trihexyphenidyl
TL;DR: Trihexyphenidyl (CAS 144-11-6) is a chemical compound with molecular formula C20H31NO and molecular weight 301.24057 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
1-cyclohexyl-1-phenyl-3-piperidin-1-ylpropan-1-ol
Also Known As: trihexyphenidyl, Benzhexol, Triphenidyl, Trihexyphenidyle, Benzhexolum
Application Areas
Top 5 of 15 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C20H31NO |
| Molecular Weight | 301.24057 g/mol |
| XLogP | 4.5 |
| Topological Polar Surface Area (TPSA) | 23.5 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 5 |
| Exact Mass | 301.24057 Da |
| Heavy Atoms | 22 |
| Complexity | 314.0 |
| Melting Point | 115 |
| Solubility | Crystals; decomp at 258.5 °C; pH of 1% aq soln 5.5-6.0; solubility (g/100 mL): water at 25 °C 1.0, alcohol 6, chloroform 5; more soluble in methanol; very slightly soluble in ether, benzene /Hydrochloride/ |
| SMILES | C1CCC(CC1)C(CCN2CCCCC2)(C3=CC=CC=C3)O |
| InChIKey | HWHLPVGTWGOCJO-UHFFFAOYSA-N |
Product Description
Applications: Trihexyphenidyl is used in pharmaceutical synthesis routes and API production, as well as biotechnology workflows and life-science research. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
Trihexyphenidyl is a pharmaceutical intermediate identified by CAS number 144-11-6 and the molecular formula C20H31NO and a molecular weight of 301.24 g/mol. Physically, the compound has a solubility: Crystals; decomp at 258.5 °C; pH of 1% aq soln 5.5-6.0; solubility (g/100 mL): water at 25 °C 1.0, alcohol 6, chloroform 5; more soluble in methanol; very slightly soluble in ether, benzene /Hydrochloride/. Synonyms include trihexyphenidyl and Benzhexol.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Trihexyphenidyl
Property Insights of Trihexyphenidyl
The XLogP value of 4.5 indicates that Trihexyphenidyl is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 23.5 Ų, Trihexyphenidyl exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Trihexyphenidyl has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Trihexyphenidyl?
The CAS number of Trihexyphenidyl is 144-11-6.
What is the molecular formula of Trihexyphenidyl?
The molecular formula of Trihexyphenidyl is C20H31NO.
What is the molecular weight of Trihexyphenidyl?
The molecular weight of Trihexyphenidyl is 301.24057 g/mol.
What are the applications of Trihexyphenidyl?
Trihexyphenidyl is used in pharmaceutical synthesis routes and API production, as well as biotechnology workflows and life-science research. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to...
Where can I buy Trihexyphenidyl?
You can request a quote for Trihexyphenidyl directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Trihexyphenidyl?
Yes, CoreyChem provides custom synthesis services for Trihexyphenidyl and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.