Nitrazepam
TL;DR: Nitrazepam (CAS 146-22-5) is a chemical compound with molecular formula C15H11N3O3 and molecular weight 281.08005 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
7-nitro-5-phenyl-1,3-dihydro-1,4-benzodiazepin-2-one
Also Known As: nitrazepam, Benzalin, Radedorm, Mogadon, Neuchlonic
Application Areas
Top 5 of 15 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C15H11N3O3 |
| Molecular Weight | 281.08005 g/mol |
| XLogP | 2.2 |
| Topological Polar Surface Area (TPSA) | 87.3 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 1 |
| Exact Mass | 281.08005 Da |
| Heavy Atoms | 21 |
| Complexity | 452.0 |
| Melting Point | 225 |
| Solubility | 2.99e-02 g/L |
| SMILES | C1C(=O)NC2=C(C=C(C=C2)[N+](=O)[O-])C(=N1)C3=CC=CC=C3 |
| InChIKey | KJONHKAYOJNZEC-UHFFFAOYSA-N |
Product Description
Applications: Nitrazepam is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies Nitrazepam (CAS 146-22-5) with custom synthesis available from milligram to multi-kilogram scale, supported by COA, MSDS, and HPLC/NMR/MS documentation.
A pharmaceutical intermediate supplied by CoreyChem, Nitrazepam (CAS 146-22-5) has the molecular formula C15H11N3O3 and a molecular weight of 281.08 g/mol. Reported properties include a solubility: 2.99e-02 g/L. It is also known as nitrazepam and Benzalin.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Nitrazepam
Property Insights of Nitrazepam
The XLogP value of 2.2 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Nitrazepam. The TPSA of 87.3 Ų falls within the moderate polarity range, balancing permeability and solubility for Nitrazepam. Following Lipinski's Rule of Five, Nitrazepam has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Nitrazepam?
The CAS number of Nitrazepam is 146-22-5.
What is the molecular formula of Nitrazepam?
The molecular formula of Nitrazepam is C15H11N3O3.
What is the molecular weight of Nitrazepam?
The molecular weight of Nitrazepam is 281.08005 g/mol.
What are the applications of Nitrazepam?
Nitrazepam is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies Nitrazepam (CAS 146-22-5) with custom...
Where can I buy Nitrazepam?
You can request a quote for Nitrazepam directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Nitrazepam?
Yes, CoreyChem provides custom synthesis services for Nitrazepam and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.